DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub85D and Tube1

DIOPT Version :9

Sequence 1:	NP_524290.2	Gene:	betaTub85D / 41124	FlyBaseID:	FBgn0003889	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_082282.1	Gene:	Tube1 / 71924	MGIID:	1919174	Length:	475	Species:	Mus musculus

Alignment Length:	458	Identity:	145/458 - (31%)
Similarity:	237/458 - (51%)	Gaps:	40/458 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCI--------DATGTYYGDSDLQLERINVYYNEATGA 57
            |.:.|.:|.||||||||..||::...||..        ||..:::.:.|.:........::...:
Mouse     1 MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDDAISSFFRNVDTRAVGDGGSISKGRIS 65

  Fly    58 KYVPRAILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRK 122
            ....||:|:|:|.|.::.:..|....:|.....:...||:|||||.||...|....:.:|:.:||
Mouse    66 SLKARAVLIDMEEGVVNEILQGPLRDVFDSKQLITDISGSGNNWAVGHKVFGCLYREQILEKLRK 130

  Fly   123 ESEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATL 187
            .:|.|||||.|.:.||:|||||||:||.|:..:.:|:|:......:|.||.: .|.:..|||:.|
Mouse   131 SAEQCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTAVYPSSE-DDVITSPYNSML 194

  Fly   188 SVHQLVENTDETYCIDNEALYDI---------------CFRTLKLTTPTYG-----------DLN 226
            ::.:|.|:.|....|||::|:||               ..:...|.|...|           .:|
Mouse   195 AMKELNEHADCVLPIDNQSLFDIISKIDLVVNSGKLGSAVKPKSLITSNMGAVKKHHKKPFDAMN 259

  Fly   227 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQ 291
            ::|:..:..:|:..||.|.||.||.::::|:||||:||:.:....||.:..........:.::..
Mouse   260 NIVANLLLSLTSSARFEGSLNMDLNEISMNLVPFPKLHYLVSSLTPLYTLADVNIPPRRLDQMFS 324

  Fly   292 QMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQN-KNSSFFVEWIPNNCKTAVCD 355
            ..|...:.:...||||..||..|.|.||.:   ::.:...||:. |.:..||.|.....||::|.
Mouse   325 DAFSKDHQLIQADPRHSLYLACALIVRGNV---QISDLRRNIERLKPALQFVSWNQEGWKTSLCS 386

  Fly   356 IPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLV 419
            :||.|...|...:.|:|.::..|..:.|:||.::::||.||.|.. :||:|..||||.|:::.|:
Mouse   387 VPPVGHSHSLLALANNTCVKPTFMELRERFTRLYKKKAHLHHYLQVDGMEESTFTEAVSSLSALI 451

  Fly   420 SEY 422
            .||
Mouse   452 QEY 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	145/458 (32%)
Tube1	NP_082282.1	epsilon_tubulin	2..457	CDD:276959	144/457 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810