Protein Alignment betaTub85D and TUBD1

DIOPT Version :9

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_057345.2
• Gene: TUBD1 / 51174
• HGNCID: 16811
• Length: 453
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 116/474 - (24%)
• Similarity: 209/474 - (44%)
• Gaps: 81/474 - (17%)

  Fly     4 IVHIQAGQCGNQIGGKFWE-VISDEHCIDATGTYYGDSDLQLERINVYYNEATGAKYVPRAILVD 67
            ||.:|.||||||||.:.:: ::||.|......:...:...|......:::|......:.||:|||
Human     3 IVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCSMRENEAYQASCKERFFSEEENGVPIARAVLVD 67

  Fly    68 LEPGTMDSVRSGA--FGQIFRPDNFVFGQ-------SGAGNNWAKGHYTEGAELVDSVLDVVRKE 123
            :||..::.:.|.|  .||      :.:||       .|:|||||.|:...|....:|:::::|||
Human    68 MEPKVINQMLSKAAQSGQ------WKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMNIIRKE 126

  Fly   124 SEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVVPSPKVSDTVVEPYNATL 187
            .|.||...||.:..|:.||||||:|..:...:.::|.:.: ||  .::......:.:|:.||:.|
Human   127 VEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMN--QIIWPYGTGEVIVQNYNSIL 189

  Fly   188 SVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNAD--- 249
            ::..|..::|.....:|:|::.||.:.:.:...::.|:|.:::..:..|     |....:|:
Human   190 TLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSV-----FQPTYSAESSF 249

  Fly   250 ------LRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALT----VPELTQQMFDAKNMMAACD 304
                  |..|..::||.|..........|..|..|..|...|    :..|.|.:.....|....|
Human   250 HYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQMLISNAKMEEGID 314

  Fly   305 PRH----------------------GRYLTVAAIFRGRMSMKEVDEQMLNIQN-KNSSFFVEWI- 345
             ||                      ...:....|.||:      |.|..:::. |:.:.:..|:
Human   315 -RHVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGK------DVQSADVEGFKDPALYTSWLK 372

  Fly   346 PNNC----KTAVCDIPPRGL---KMSATFIGNSTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGM 403
            |.|.    ||      .|..   :.||..:.||..:.:....:..:...||..||::|.||..|:
Human   373 PVNAFNVWKT------QRAFSKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGI 431

  Fly   404 DEMEFTEAESNMNDLVSEY 422
            :|.:|.::.:::..:|:.|
Human   432 EEEDFLDSFTSLEQVVASY 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	116/474 (24%)
TUBD1	NP_057345.2	delta_zeta_tubulin-like	2..452	CDD:276958	116/474 (24%)
		Tubulin	2..213	CDD:278518	65/217 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810