Protein Alignment betaTub85D and TUBB8

DIOPT Version :9

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_817124.1
• Gene: TUBB8 / 347688
• HGNCID: 20773
• Length: 444
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 392/446 - (87%)
• Similarity: 419/446 - (93%)
• Gaps: 4/446 - (0%)

  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDLQLERINVYYNEATGAKYVPRAIL 65
            |||||..|.||||||||.||||||||||.||:.|||:|||.|||||||||||||:|.:|||||:|
Human     1 MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGGRYVPRAVL 65

  Fly    66 VDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCDCL 130
            ||||||||||||||.|||:||||||:|||.|||||||||||||||||::||:||||||:|.||||
Human    66 VDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCL 130

  Fly   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVEN 195
            |||||||||||||||||||||:|||||||||||:||||::||||||||||||||||||||||:||
Human   131 QGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIEN 195

  Fly   196 TDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260
            .|||:|||||||||||.:||||.||||||||||||||||||||||||||||||||||||||||||
Human   196 ADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260

  Fly   261 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKE 325
            ||||||||||||||||||||||||||.|||||||||||||||||||||||||.||||||||.|:|
Human   261 PRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRGRMPMRE 325

  Fly   326 VDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFR 390
            |||||.|||:||||:|.:|:|||.|||||||||||||||||||||:|||||||||||||||||||
Human   326 VDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQFTAMFR 390

  Fly   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEEGGGDE 446
            ||||||||||||||||||||||||||||||||||||:|||:||    ||||...:|
Human   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEE----EDEEYAEEE 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	383/428 (89%)
TUBB8	NP_817124.1	PTZ00010	1..427	CDD:240228	381/425 (90%)
		beta_tubulin	2..426	CDD:276956	379/423 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		14/24 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.830