Protein Alignment betaTub85D and Tuba1a

DIOPT Version :10

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_035783.1
• Gene: Tuba1a / 22142
• MGIID: 98869
• Length: 451
• Species: Mus musculus
• Alignment Length: 455
• Identity: 182/455 - (40%)
• Similarity: 270/455 - (59%)
• Gaps: 19/455 - (4%)

  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATG------TYYGDSDLQLERINVYYNEATGAKY 59
            |||.:.|..||.|.|||...||:...||.|...|      |..|..|    ..|.:::|....|:
Mouse     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDD----SFNTFFSETGAGKH 61

  Fly    60 VPRAILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKES 124
            ||||:.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|::|.|||.:||.:
Mouse    62 VPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLA 126

  Fly   125 EGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSV 189
            :.|..||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.
Mouse   127 DQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTT 191

  Fly   190 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254
            |..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:..
Mouse   192 HTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQ 256

  Fly   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRG 319
            .|:||:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|..||||||:|:....::||
Mouse   257 TNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRG 321

  Fly   320 RMSMKEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPP--------RGLKMSATFIGNSTAIQE 376
            .:..|:|:..:..|:.|.:..||:|.|...|..:...||        ..::.:...:.|:|||.|
Mouse   322 DVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386

  Fly   377 LFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEE 441
            .:.|:..:|..|:.::||:|||.||||:|.||:||..:|..|..:|::....:.:.||| :|.||
Mouse   387 AWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGE-EEGEE 450

  Fly   442  441
            Mouse   451  450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	176/442 (40%)
Tuba1a	NP_035783.1	PTZ00335	1..440	CDD:185562	176/442 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		7/20 (35%)