Protein Alignment betaTub85D and mec-12

DIOPT Version :9

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_497663.1
• Gene: mec-12 / 175419
• WormBaseID: WBGene00003175
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 456
• Identity: 175/456 - (38%)
• Similarity: 270/456 - (59%)
• Gaps: 17/456 - (3%)

  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDL--QLERINVYYNEATGAKYVPRA 63
            |||::.|..||.|.|||...||:...||.|...|....|..|  ..:..:.:::|....::||||
 Worm     1 MREVISIHIGQAGVQIGNACWELYCLEHGIQPDGQMPSDKSLGGSDDSFSTFFSETGSGRHVPRA 65

  Fly    64 ILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCD 128
            ::|||||..:|.:|:|.:..:|.|:..:.|:..|.||:|:||||.|.|::|..||.:|:.::.|.
 Worm    66 VMVDLEPTVIDEIRTGTYRSLFHPEQLITGKEDAANNYARGHYTIGKEIIDLTLDRIRRLADNCT 130

  Fly   129 CLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLV 193
            .||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|..:
 Worm   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKAKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   194 ENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMV 258
            |::|.::.:||||:||||.|.|.:..|:|.:||.|:...:|.:|..|||.|.||.||.:...|:|
 Worm   196 EHSDCSFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   259 PFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSM 323
            |:||:||.:..|:|:.|.....:..|:|.|:|...|:..|.|..||||||:|:.|..:|||.:..
 Worm   261 PYPRIHFPLATFSPVISAEKAYHEQLSVAEITNMCFEPHNQMVKCDPRHGKYMAVCLLFRGDVVP 325

  Fly   324 KEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPP--------RGLKMSATFIGNSTAIQELFKR 380
            |:|:..:..|:.|.|..||:|.|...|..:...||        ..:..:...:.|:|||.|.:.|
 Worm   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVPRAVCMLSNTTAIAEAWAR 390

  Fly   381 VSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEEGGGD 445
            :..:|..|:.::||:|||.||||:|.||:||..::..|..:|::....:.::.||       .||
 Worm   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSMEDNGE-------EGD 448

  Fly   446 E 446
            |
 Worm   449 E 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	170/438 (39%)
mec-12	NP_497663.1	PTZ00335	1..448	CDD:185562	172/453 (38%)
		alpha_tubulin	2..435	CDD:276955	169/432 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810