Protein Alignment betaTub85D and TUBA3E

DIOPT Version :9

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_997195.2
• Gene: TUBA3E / 112714
• HGNCID: 20765
• Length: 450
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 180/455 - (39%)
• Similarity: 265/455 - (58%)
• Gaps: 22/455 - (4%)

  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATG------TYYGDSDLQLERINVYYNEATGAKY 59
            |||.:.|..||.|.|||...||:...||.|...|      |..|..|    ..|.:::|....|:
Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDD----SFNTFFSETGAGKH 61

  Fly    60 VPRAILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKES 124
            ||||:.|||||..:|.||:|.:.|:|.|:..:.|:..|.:|:|:||||.|.|:||.|||.:||.:
Human    62 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLDRIRKLA 126

  Fly   125 EGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSV 189
            :.|..||||.:.||.|||||||..:||:.::..:|..:....|::.|:|:||..||||||:.|:.
Human   127 DLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTAVVEPYNSILTT 191

  Fly   190 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254
            |..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:..
Human   192 HTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQ 256

  Fly   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRG 319
            .|:||:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|..||||||:|:....::||
Human   257 TNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRG 321

  Fly   320 RMSMKEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPP--------RGLKMSATFIGNSTAIQE 376
            .:..|:|:..:..|:.|.:..||:|.|...|..:...||        ..::.:...:.|:|||.|
Human   322 DVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386

  Fly   377 LFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADE-EGEFDEDE 440
            .:.|:..:|..|:.:.||:|||.||||:|.||:||.   .||.:..:..:|...|. |.|.:|.|
Human   387 AWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSEAR---EDLAALEKDCEEVGVDSVEAEAEEGE 448

  Fly   441  440
            Human   449  448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	175/442 (40%)
TUBA3E	NP_997195.2	PTZ00335	1..440	CDD:185562	176/445 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810