Protein Alignment CG8135 and Lmbrd2

DIOPT Version :10

• Sequence 1: NP_649890.1
• Gene: CG8135 / 41123
• FlyBaseID: FBgn0037689
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_001102647.1
• Gene: Lmbrd2 / 499539
• RGDID: 1563920
• Length: 694
• Species: Rattus norvegicus
• Alignment Length: 733
• Identity: 310/733 - (42%)
• Similarity: 435/733 - (59%)
• Gaps: 87/733 - (11%)

  Fly     5 LSFGIVAALFLASISLYRYGNIPRQHILVTLSVLTAWCFSFLIVFTIPLDVTSTLYRQCVEEHRP 69
            |...||...|||...|:|||:..:||.||.:..|.||...|||||.:||||::|:|.:|......
  Rat     6 LGLEIVFVFFLALFLLHRYGDFKKQHRLVIVGTLLAWYLCFLIVFILPLDVSTTIYNRCRHAAAN 70

  Fly    70 TPAPNVTNTSS--ATVGPPPQ---CQEPWGMVPASVFPNLWRIIYWSSQFLTWLIMPLMQSYLKA 129
            :..|..:|.:.  |:|.|..:   |.:||..:|..:.|..||::||:||||||:::|.||||.::
  Rat    71 SSPPENSNVTGVYASVTPAQRQHPCFKPWSYIPDGIMPIFWRVVYWTSQFLTWILLPFMQSYARS 135

  Fly   130 GDFTVKGKLKSALIENAIYYGSYLFICGVLLIYIAVKGE-SLDWQKLKAIASSASNTWGLFLLIL 193
            |.|::.||:|:||||||||||:||.|.|..|||:||... .|:|.:|:.|..:|:||||||||:|
  Rat   136 GGFSITGKIKTALIENAIYYGTYLLIFGAFLIYVAVNPRLHLEWNQLQTIGIAAANTWGLFLLVL 200

  Fly   194 LLGYALVEVPRSLWNNAKPGFALQYAYFKAAKLSTEKAEAEEHVDDILESLQGLSRVIPNNHELR 258
            ||||.|||:|||.||.||.|:.|...|||||||.||||:|||:::|::|.::.::..|..||.||
  Rat   201 LLGYGLVEIPRSYWNGAKRGYLLMKTYFKAAKLMTEKADAEENLEDVMEEVRKVNESIKYNHPLR 265

  Fly   259 PCLETILRKVPIELQERASRN------FARTGGSGMGATSSTILPSEKALVRIHKQVIKSLQTLQ 317
            .|::|||:|.|.:.||:..||      |..         .....||||:||::|||||.|:|..:
  Rat   266 KCVDTILKKCPTDYQEKMGRNMDDYEDFDE---------KRNTYPSEKSLVKLHKQVIYSVQRHR 321

  Fly   318 RTEALWSVQVQTVLHLEDVAKNIHSSDRRFKSEF--PRQRTQLERICYSASLQWYWECLLKAPFL 380
            ||:..|.:.::...:|||||||..|:..:|...|  |....:..:..|:.:::|||||||:..|.
  Rat   322 RTQVQWQILLEQAFYLEDVAKNETSATHQFVHTFQSPEPENRFIQYFYNPTVEWYWECLLRPWFH 386

  Fly   381 KTMCVLTATMSAMVVWSELTFFSRHPVLSIFANVIYVAKESYDFFTIEVFSMVVLCYFFYCTYST 445
            :.:.|:.:..|.:|||||.||||..||||:||..|.:|:::|::..||:...:.:.:...|.|||
  Rat   387 RILAVVLSIFSVIVVWSECTFFSTTPVLSLFAVFIQLAEKTYNYIYIEIACFLSIFFLSICVYST 451

  Fly   446 ILRIRFLNLYYLAPHHQTNEHSLIFSGMLLCRLTPPMCLNFLGLIHMDTHIIPNRIMETVYTQIM 510
            :.|||..|.||||.||||:.:||:|||||.||||||:|||||||.|||..|.......|.||.||
  Rat   452 VFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDASISHQNTQPTAYTSIM 516

  Fly   511 GHMDVIGIISNGFNIYFPMCMLAFCLATWFSLGSRALNALGFQQFLQNETIATELVQEGKDLIAR 575
            |.|.|:..|::||.||:||.::..|:||:||||:|.||.||||||:.:..:.::||.|||:||.|
  Rat   517 GSMKVLSFIADGFYIYYPMLVVILCIATYFSLGTRCLNLLGFQQFMGDNDMTSDLVDEGKELIRR 581

  Fly   576 EKRRRQRAEEAMARRRDF------NRTDQVLG----------------SDYLSKYRSGGPGGLTS 618
            |||:|||.||...|||::      ||.|....                :::.|||..      .:
  Rat   582 EKRKRQRQEEGENRRREWKERYGHNREDSTRNRNVHSDPKESNFSDTTTNWSSKYTR------AN 640

  Fly   619 SRTPAD--GLLRDGDGSFDYAAVASSSALGVPRSLSEEINDRFGVSTQVQVGFRDPDYEAET--- 678
            :||..|  .||:|.:                |...:.|.             |.|...|.|:
  Rat   641 NRTERDRIELLQDAE----------------PLDFNAET-------------FTDDSLEPESGRY 676

  Fly   679 --DGRIVGPPPRGLFDDV 694
              .||.:......:|:|:
  Rat   677 QPGGRYLSMSSSIIFEDI 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8135	NP_649890.1	LMBR1	1..543	CDD:461429	258/551 (47%)
Lmbrd2	NP_001102647.1	LMBR1	22..549	CDD:461429	251/535 (47%)