DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9356 and Blzf1

DIOPT Version :9

Sequence 1:NP_649889.1 Gene:CG9356 / 41122 FlyBaseID:FBgn0037688 Length:448 Species:Drosophila melanogaster
Sequence 2:NP_079781.2 Gene:Blzf1 / 66352 MGIID:1201607 Length:410 Species:Mus musculus


Alignment Length:405 Identity:104/405 - (25%)
Similarity:164/405 - (40%) Gaps:84/405 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 KRPQLSRKDSSVVQEAVMGRKTSTSSGHSSNLPLPGLHTLYRRPE-----NVTRSLAPVVPKGEL 109
            |...|...::...||.:.|..|||        |:.|........|     .||..:.|:   .:.
Mouse     3 KMTTLKSSENKGKQEMMKGILTST--------PIRGAGDGMETEEPPKSVEVTHGVQPI---NQH 56

  Fly   110 VQMRPRLVTSADSLPEHKKTKAPKFVPYEPYPGAVNPMISEPTNKHKIHRDKNNLDIAVLVDQVS 174
            |...||...|:||                  ||.:  .:.:..|:..:..:.    :.:.|.:.:
Mouse    57 VLPSPRKKVSSDS------------------PGVL--QLGKILNERTVEVEA----VRIFVPKAA 97

  Fly   175 TLRTQELETETTDIK-------------ETDTASSHEVNSLKEELAKMRD-ERNYFQ------AQ 219
            .  |.::.|:.|.:|             |..|....|::.:|:.|.|::: ||...|      .|
Mouse    98 I--THDIPTKNTKVKSLGHHREELHNQAEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQ 160

  Fly   220 YKFQTQVNSELKSLLVASVGEDLQTRVNLLTEDKLQLARALLDTANNLTTHTEQIEFLAGQCEVW 284
            .:.||::|.|||.|||||||:|.|.....|..:|.||.........|....:||:|.::.||:||
Mouse   161 LRVQTEINRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVW 225

  Fly   285 RSKFLASSVMVEELARWKADLTQKNQLLNESTKQLLHATHQIREIQLDMLKQLKFLAKIRFL--- 346
            |||||||.||.:||..::..|.::|:....:.:.||....|.|:   :|....|||.::...   
Mouse   226 RSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQ---EMTSTQKFLEELLVSLQW 287

  Fly   347 --------NLPATDVISLSAENLNILQRMVLHT--GVGIPEETLKLSSASTSPLCE--AEKYAVR 399
                    |........|:..|..:.|.:..|.  .|||..:.   ...:|...|.  |||.|.:
Mouse   288 GREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQK---KIPTTVEFCSTPAEKMAEK 349

  Fly   400 ALEFISQPLMATDEA 414
            .|. |..|:..|:.:
Mouse   350 VLR-ILDPVACTESS 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9356NP_649889.1 SMC_prok_B <156..>333 CDD:274008 59/196 (30%)
Blzf1NP_079781.2 Tankyrase-binding motif. /evidence=ECO:0000250|UniProtKB:Q9H2G9 29..33 1/3 (33%)
DASH_Hsk3 191..236 CDD:285441 19/44 (43%)
Essential for interaction with GORASP2. /evidence=ECO:0000269|PubMed:28049725 404..410
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167840854
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4074
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0006490
OrthoInspector 1 1.000 - - oto94685
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR13066
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3881
SonicParanoid 1 1.000 - - X6227
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1110.830

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