DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9356 and Blzf1

DIOPT Version :9

Sequence 1:	NP_649889.1	Gene:	CG9356 / 41122	FlyBaseID:	FBgn0037688	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001017494.1	Gene:	Blzf1 / 498266	RGDID:	1562452	Length:	400	Species:	Rattus norvegicus

Alignment Length:	428	Identity:	107/428 - (25%)
Similarity:	163/428 - (38%)	Gaps:	116/428 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SQACRTSGDGMEQPENSGAAKTESEIPASADVDNKVKRPQLSRKDSSVVQEAVM--GRKTSTSSG 76
            |...|.:|||||         || |.|.|.:|.:.|:          .:.:.|:  .||...|..
  Rat    18 STPIRGAGDGME---------TE-EPPKSVEVTHGVQ----------PINQHVLPSPRKKVPSDS 62

  Fly    77 HSSNLPLPGLHTLYRRPENVTRSLAPV---VPKGELVQMRPRLVTSADSLPEHKKTKAPKFVPYE 138
                   ||:..|.:.....|..:..|   |||..:....|.......||..|:
  Rat    63 -------PGVLQLGKILNEKTVEVEAVRIFVPKAAITHDIPTKSAKVKSLGHHR----------- 109

  Fly   139 PYPGAVNPMISEPTNKHKIHRDKNNLDIAVLVDQVSTLRTQELETETTDIKETDTASSHEVNSLK 203
                                                    :||..::    |..|....|::.:|
  Rat   110 ----------------------------------------EELHNQS----EVVTDPRKELSEVK 130

  Fly   204 EELAKMRD-ERNYFQ------AQYKFQTQVNSELKSLLVASVGEDLQTRVNLLTEDKLQLARALL 261
            :.|.|::: ||...|      .|.:.||:||.|||.|||||||:|.|.....|..:|.||.....
  Rat   131 KVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDPQYHFERLAREKNQLILENE 195

  Fly   262 DTANNLTTHTEQIEFLAGQCEVWRSKFLASSVMVEELARWKADLTQKNQLLNESTKQLLHATHQI 326
            ....|....:||:|.::.||:|||||||||.||.:||..::..|..:|:....:.:.||....|.
  Rat   196 ALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQHQNRDAQSAIQDLLSEREQF 260

  Fly   327 REIQLDMLKQLKFLAKIRFL-----------NLPATDVISLSAENLNILQRMVLH----TGVGIP 376
            |:   :|:...|||.::...           |........|:..|..:.:.:..|    .|:..|
  Rat   261 RQ---EMISTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHRLAEAVHAHLLGNVGISHP 322

  Fly   377 EETLKLSSASTSPLCEAEKYAVRALEFISQPLMATDEA 414
            :.|...:...::|   |||.|.:.|. |..|:..|:.:
  Rat   323 KRTPATAEVCSTP---AEKMAEKVLR-ILDPVACTESS 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9356	NP_649889.1	SMC_prok_B	<156..>333	CDD:274008	57/183 (31%)
Blzf1	NP_001017494.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36		11/27 (41%)
		Tankyrase-binding motif. /evidence=ECO:0000250\|UniProtKB:Q9H2G9	22..26		1/3 (33%)
		UPF0242	100..>254	CDD:311007	56/208 (27%)
		DASH_Hsk3	184..229	CDD:311925	19/44 (43%)
		Essential for interaction with GORASP2. /evidence=ECO:0000250\|UniProtKB:Q9H2G9	394..400
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344269
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4074
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5018
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1218216at2759
OrthoFinder	1	1.000	-	-		FOG0006490
OrthoInspector	1	1.000	-	-		oto98192
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13066
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.900