DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8132 and BTD

DIOPT Version :9

Sequence 1:	NP_649888.1	Gene:	CG8132 / 41121	FlyBaseID:	FBgn0037687	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001268652.2	Gene:	BTD / 686	HGNCID:	1122	Length:	523	Species:	Homo sapiens

Alignment Length:	139	Identity:	40/139 - (28%)
Similarity:	65/139 - (46%)	Gaps:	34/139 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 QQLSNLARKHQVYIVG--GT----------IPELGENDAIYNTCTVWSPTGDLVAKHRKMHL--- 122
            |:||.:|.:..:::|.  ||          .|:.|...  :||..|:|..|.||.::||.:|
Human   136 QRLSCMAIRGDMFLVANLGTKEPCHSSDPRCPKDGRYQ--FNTNVVFSNNGTLVDRYRKHNLYFE 198

  Fly   123 --FDIDVKGGIRFKESETLSAGNDFTIINVDGHKIGIGICYDIRFEEMA-RLYRNAGCEMIIYPA 184
              ||:.:|  :.....:|..||           :.||..|:||.|.:.| |:.|:...:.::||.
Human   199 AAFDVPLK--VDLITFDTPFAG-----------RFGIFTCFDILFFDPAIRVLRDYKVKHVVYPT 250

  Fly   185 AFNMTTGPL 193
            |: |...||
Human   251 AW-MNQLPL 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8132	NP_649888.1	nit	9..272	CDD:143596	40/139 (29%)
BTD	NP_001268652.2	biotinidase_like	38..341	CDD:143591	40/139 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810