Protein Alignment CG8132 and NIT2

DIOPT Version :10

• Sequence 1: NP_649888.1
• Gene: CG8132 / 41121
• FlyBaseID: FBgn0037687
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: XP_054203250.1
• Gene: NIT2 / 56954
• HGNCID: 29878
• Length: 381
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 152/276 - (55%)
• Similarity: 203/276 - (73%)
• Gaps: 9/276 - (3%)

  Fly     9 RLALLQLKGSKDKVANVQNAVTKI-EAAVKEHKPRLITLPECFNAPYGTKYFREYSETIPDGYTS 72
            ||||:||:.|..|..||..|.:.| |||.:..|  :::||||||:|||.|||.||:|.|| |.::
Human   110 RLALIQLQISSIKSDNVTRACSFIREAATQGAK--IVSLPECFNSPYGAKYFPEYAEKIP-GEST 171

  Fly    73 QQLSNLARKHQVYIVGGTIPELGENDA--IYNTCTVWSPTGDLVAKHRKMHLFDIDVKGGIRFKE 135
            |:||.:|::..:|::||:||   |.||  :||||.|:.|.|.|:||:||:|||||||.|.|.|:|
Human   172 QKLSEVAKECSIYLIGGSIP---EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQE 233

  Fly   136 SETLSAGNDFTIINVDGHKIGIGICYDIRFEEMARLYRNAGCEMIIYPAAFNMTTGPLHWELLQR 200
            |:|||.|:.|:..:....::|:|||||:||.|:|::|...||::::||.|||:||||.|||||||
Human   234 SKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQR 298

  Fly   201 SRANDNQLFVVTTSPARDTSAEYVAYGHSMVVNPWAKVQQSASEGEEIVVADIDFSEVEQVRQQI 265
            |||.|||::|.|.|||||..|.|||:|||.|||||.:|...|...|.||.:|||..::.::||||
Human   299 SRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEAIVYSDIDLKKLAEIRQQI 363

  Fly   266 PVFGQRRLDLYATERK 281
            |||.|:|.||||.|.|
Human   364 PVFRQKRSDLYAVEMK 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8132	NP_649888.1	nit	9..272	CDD:143596	145/265 (55%)
NIT2	XP_054203250.1	nit	110..370	CDD:143596	145/265 (55%)