DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8132 and nit2

DIOPT Version :9

Sequence 1:	NP_649888.1	Gene:	CG8132 / 41121	FlyBaseID:	FBgn0037687	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_991174.3	Gene:	nit2 / 402904	ZFINID:	ZDB-GENE-050522-65	Length:	284	Species:	Danio rerio

Alignment Length:	278	Identity:	151/278 - (54%)
Similarity:	196/278 - (70%)	Gaps:	9/278 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKTSNIMRLALLQLKGSKDKVANVQNAVTKI-EAAVKEHKPRLITLPECFNAPYGTKYFREYSE 64
            |||    .|||::||..||.|..|:..|.|.: |||.:..|  ::.||||||:||||.:|:||:|
Zfish     8 MSK----FRLAVVQLHVSKIKADNLGRAQTLVTEAAGQGAK--VVVLPECFNSPYGTGFFKEYAE 66

  Fly    65 TIPDGYTSQQLSNLARKHQVYIVGGTIPELGENDAIYNTCTVWSPTGDLVAKHRKMHLFDIDVKG 129
            .|| |.::|.||..|:|..:|:|||:||| .:...:||||:|:.|.|.|:..|||:|||||||.|
Zfish    67 KIP-GESTQVLSETAKKCGIYLVGGSIPE-EDGGKLYNTCSVFGPDGKLLVTHRKIHLFDIDVPG 129

  Fly   130 GIRFKESETLSAGNDFTIINVDGHKIGIGICYDIRFEEMARLYRNAGCEMIIYPAAFNMTTGPLH 194
            .|||:||||||.|...::......|:|:||||||||.|:|::|...||::::||.||||||||.|
Zfish   130 KIRFQESETLSPGKSLSMFETPYCKVGVGICYDIRFAELAQIYAKKGCQLLVYPGAFNMTTGPAH 194

  Fly   195 WELLQRSRANDNQLFVVTTSPARDTSAEYVAYGHSMVVNPWAKVQQSASEGEEIVVADIDFSEVE 259
            ||||||.||.|||::|.|.|||||.:|.|||:|||.|:|||.:|...|...|.:|.||||...:.
Zfish   195 WELLQRGRAVDNQVYVATASPARDETASYVAWGHSSVINPWGEVISKAGSEESVVYADIDLQYLA 259

  Fly   260 QVRQQIPVFGQRRLDLYA 277
            .||||||:..|||.|||:
Zfish   260 DVRQQIPITKQRRNDLYS 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8132	NP_649888.1	nit	9..272	CDD:143596	143/263 (54%)
nit2	NP_991174.3	nit	12..272	CDD:143596	143/263 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594471
Domainoid	1	1.000	280	1.000	Domainoid score	I1652
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6520
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2715
OMA	1	1.010	-	-		QHG62384
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	1	1.000	-	-		FOG0001670
OrthoInspector	1	1.000	-	-		oto41360
orthoMCL	1	0.900	-	-		OOG6_100517
Panther	1	1.100	-	-	LDO	PTHR23088
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1707
SonicParanoid	1	1.000	-	-		X1563
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800