DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8132 and Nit2

DIOPT Version :9

Sequence 1:	NP_649888.1	Gene:	CG8132 / 41121	FlyBaseID:	FBgn0037687	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_038944121.1	Gene:	Nit2 / 288174	RGDID:	1310494	Length:	360	Species:	Rattus norvegicus

Alignment Length:	274	Identity:	142/274 - (51%)
Similarity:	202/274 - (73%)	Gaps:	5/274 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RLALLQLKGSKDKVANVQNAVTKIEAAVKEHKPRLITLPECFNAPYGTKYFREYSETIPDGYTSQ 73
            ||||:||:.|..|..|:..|.:.:..|.|: ...:::||||||:||||.||.||:|.|| |.:::
  Rat    89 RLALIQLQVSSIKSDNITRACSLVREAAKQ-GANIVSLPECFNSPYGTNYFPEYAEKIP-GESTK 151

  Fly    74 QLSNLARKHQVYIVGGTIPELGENDA-IYNTCTVWSPTGDLVAKHRKMHLFDIDVKGGIRFKESE 137
            :||.:|:::.:|::||:|||  |:|. :||||.|:.|.|:|:.||||:|||||||.|.|.|:||:
  Rat   152 KLSEVAKENSIYLIGGSIPE--EDDGKLYNTCAVFGPDGNLLVKHRKIHLFDIDVPGKITFQESK 214

  Fly   138 TLSAGNDFTIINVDGHKIGIGICYDIRFEEMARLYRNAGCEMIIYPAAFNMTTGPLHWELLQRSR 202
            |||.|:.|:..:....::|:|||||:||.|:|::|...||::::||.||||||||.|||||||:|
  Rat   215 TLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYARRGCQLLVYPGAFNMTTGPAHWELLQRAR 279

  Fly   203 ANDNQLFVVTTSPARDTSAEYVAYGHSMVVNPWAKVQQSASEGEEIVVADIDFSEVEQVRQQIPV 267
            |.|||::|.|.|||||..|.|||:|||.||:||.:|...|...|.|:.:|||..::.::|||||:
  Rat   280 AVDNQVYVATASPARDEKASYVAWGHSTVVDPWGQVLTKAGTEETILYSDIDLKKLSEIRQQIPI 344

  Fly   268 FGQRRLDLYATERK 281
            ..|:|.|||:.|.|
  Rat   345 LKQKRADLYSVESK 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8132	NP_649888.1	nit	9..272	CDD:143596	136/263 (52%)
Nit2	XP_038944121.1	nit	89..349	CDD:143596	136/263 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352526
Domainoid	1	1.000	280	1.000	Domainoid score	I1606
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6520
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2600
OMA	1	1.010	-	-		QHG62384
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	1	1.000	-	-		FOG0001670
OrthoInspector	1	1.000	-	-		oto97982
orthoMCL	1	0.900	-	-		OOG6_100517
Panther	1	1.100	-	-	LDO	PTHR23088
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1563
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770