DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8132 and nft-1

DIOPT Version :9

Sequence 1:	NP_649888.1	Gene:	CG8132 / 41121	FlyBaseID:	FBgn0037687	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_499556.1	Gene:	nft-1 / 176628	WormBaseID:	WBGene00003594	Length:	440	Species:	Caenorhabditis elegans

Alignment Length:	284	Identity:	98/284 - (34%)
Similarity:	147/284 - (51%)	Gaps:	32/284 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LALLQLKGSKDKVANVQNAVTKIEAAVKEHKPRLITLPECFN-------------APYGTKYFRE 61
            :|:.|:....|...|.|.|...||.| .|.|..::.|||||:             .....:|..:
Worm    17 IAVCQMTSDNDLEKNFQAAKNMIERA-GEKKCEMVFLPECFDFIGLNKNEQIDLAMATDCEYMEK 80

  Fly    62 YSETIPDGYTSQQLSNLARKHQVYIVGGTIPELGENDAI--YNTCTVWSPTGDLVAKHRKMHLFD 124
            |.|             |||||.:::..|.:.....:||.  :||..:....|...|::.|:||||
Worm    81 YRE-------------LARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHLFD 132

  Fly   125 IDVKGGIRFKESETLSAGNDFTIINVDG--HKIGIGICYDIRFEEMARLYRNAGCEMIIYPAAFN 187
            :::.|.:|..|||...||.:. |..||.  .::|:.||||:||.|::...|..|.:::.:|:||.
Worm   133 LEIPGKVRLMESEFSKAGTEM-IPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLSFPSAFT 196

  Fly   188 MTTGPLHWELLQRSRANDNQLFVVTTSPARDTSAEYVAYGHSMVVNPWAKVQQSASEGEEIVVAD 252
            :.||..|||.|.|:||.:||.:||..:.....:.:..:|||||||:||..|....||..::..|:
Worm   197 LNTGLAHWETLLRARAIENQCYVVAAAQTGAHNPKRQSYGHSMVVDPWGAVVAQCSERVDMCFAE 261

  Fly   253 IDFSEVEQVRQQIPVFGQRRLDLY 276
            ||.|.|:.:|:..|||..||.|||
Worm   262 IDLSYVDTLREMQPVFSHRRSDLY 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8132	NP_649888.1	nit	9..272	CDD:143596	93/278 (33%)
nft-1	NP_499556.1	nit	17..281	CDD:143596	93/278 (33%)
nft-1	NP_499556.1	FHIT	300..418	CDD:238606
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.993157	Normalized mean entropy	S629
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154369at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770