DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and PIN3

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_015480.1	Gene:	PIN3 / 856277	SGDID:	S000006358	Length:	215	Species:	Saccharomyces cerevisiae

Alignment Length:	213	Identity:	41/213 - (19%)
Similarity:	73/213 - (34%)	Gaps:	60/213 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   569 AAVLTNTNNNHIYADLELDKKKDTSPSPECKGEQIQPKKEQIRIEINQT---------APQNSID 624
            :|.|.|.:..:|..:|:.           .||..:  ....:..:||::         ||:|:..
Yeast     2 SASLINRSLTNIRTELDF-----------LKGSNV--ISNDVYDQINKSLPAKWDPANAPRNASP 53

  Fly   625 AHLDRIDELNRV---LDDRLKRTLQPSDDVNAIESAEENHIQTRKLAKD-------------PDS 673
            |.|:.::.|.:.   .|..|  .|:|.|.|..:|          ||:.:             |.:
Yeast    54 ASLEYVEALYQFDPQQDGDL--GLKPGDKVQLLE----------KLSPEWYKGSCNGRTGIFPAN 106

  Fly   674 QTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNIFSNLKEFSKSPLVRMGKNHILNEEQDAKR 738
            ..|.:.|.|:...:.......|.:.|    :.|....|....:.:.|......|:....:|..::
Yeast   107 YVKPAFSGSNGPSNLPPPPQYKAQEL----QQIPTQNSAASSYQQQPFPPPSTNYYQQPQQQPQQ 167

  Fly   739 TQP------SQHHHSSGS 750
            ..|      .|.|.||.|
Yeast   168 APPPQQQQQQQQHQSSHS 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
PIN3	NP_015480.1	SH3	58..110	CDD:418401	11/63 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000