DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and HT1

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_176430.2	Gene:	HT1 / 842538	AraportID:	AT1G62400	Length:	390	Species:	Arabidopsis thaliana

Alignment Length:	271	Identity:	85/271 - (31%)
Similarity:	133/271 - (49%)	Gaps:	13/271 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly  1053 RERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKR-----KFLQEGRI 1112
            ||.|......:.:..:...|....:|:...|...  ||||..|:....|:.|     :|..|..:
plant    76 REEWTADLSQLFIGNKFASGAHSRIYRGIYKQRA--VAVKMVRIPTHKEETRAKLEQQFKSEVAL 138

  Fly  1113 LKQYDHPNIVKLIGICVQKQPI-MIVMELVLGGSLLTYL-RKNSNGLTTRQQMGMCRDAAAGMRY 1175
            |.:..|||||:.|..| :|.|: .|:.|.:..|:|..|| :|....|:....:.:..|.:.||.|
plant   139 LSRLFHPNIVQFIAAC-KKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEY 202

  Fly  1176 LESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSL 1240
            |.|:..|||||.:.|.|::.|..||::|||.|..|.:...:.| .....:|.|||.:....||..
plant   203 LHSQGVIHRDLKSNNLLLNDEMRVKVADFGTSCLETQCREAKG-NMGTYRWMAPEMIKEKPYTRK 266

  Fly  1241 CDVWSYGILMWEIFSKGDTPYSGMTNSRARERI-DTGYRMPTPKSTPEEMYRLMLQCWAADAESR 1304
            .||:|:||::||: :....|:.|||..:|...: :...|.|.|.|....:..|:.:||:.:...|
plant   267 VDVYSFGIVLWEL-TTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKR 330

  Fly  1305 PHFDEIYNVVD 1315
            |.|..|..|::
plant   331 PDFSNIVAVLE 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	80/255 (31%)
		PTKc_Fes_like	1067..1315	CDD:270637	82/255 (32%)
HT1	NP_176430.2	STKc_MAP3K-like	93..340	CDD:270901	81/251 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910