back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and RKF1

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_174268.7	Gene:	RKF1 / 839853	AraportID:	AT1G29750	Length:	1021	Species:	Arabidopsis thaliana

Alignment Length:	938	Identity:	199/938 - (21%)
Similarity:	345/938 - (36%)	Gaps:	288/938 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 ASVHYLG-EEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLTQLTAAVLTNTNNNHI 580
            :|:.||. |..|.|.|.|.:|..|  .....|.|..::....|  ||.|.:|..  :|:...|
plant   169 SSLTYLDLESNAFSGTIPQELGNL--VHLKKLLLSSNKLTGTL--PASLARLQN--MTDFRIN-- 225

  Fly   581 YADLELDKKKDTSPSPECKGEQIQPKKEQIRIEI---NQTAPQNSIDAHLDRIDELNRVLDDRLK 642
              ||:|   ..|.||      .||..|:..|:|:   ..|.|..|:.:.|..:..| |:.|  ::
plant   226 --DLQL---SGTIPS------YIQNWKQLERLEMIASGLTGPIPSVISVLSNLVNL-RISD--IR 276

  Fly   643 RTLQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKD----TSHSKKRSLSFSQ 703
            ..:||...:..:...      |:.:.|:              |..|..    .||.|:  |....
plant   277 GPVQPFPSLKNVTGL------TKIILKN--------------CNISGQIPTYLSHLKE--LETLD 319

  Fly   704 KSISNIFSNLKEFSKSPLVR---MGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNN 765
            .|.:.:...:..|:::..:|   :..|.:   |.||    |.:
plant   320 LSFNKLVGGIPSFAQAENLRFIILAGNML---EGDA----PDE---------------------- 355

  Fly   766 NNKNTSSNSNHSASQSTIITSTITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLL 830
                             ::...||..::          .:.||::.|    :|:|.|......|.
plant   356 -----------------LLRDGITVDLS----------YNNLKWQSP----ESRACRPNMNLNLN 389

  Fly   831 NFQLKRSK------PCKQCTKRRR----IHPSKSVFD-FAKE------FEVEQPAGSAADEQFCN 878
            .||...:|      ||.:..|..|    :|.:....| :.||      :|.:......|.:.|
plant   390 LFQSTSTKKSSKFLPCIKDFKCPRYSSCLHVNCGGSDMYVKEKKTKELYEGDGNVEGGAAKYF-- 452

  Fly   879 CPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRD--------IDNDEEEEDSASDDVLSMKD 935
                    :||..      :..|.|:...:|:|:.::        ..|..:...||....:|:..
plant   453 --------LKPDA------NWGFSSTGDFMDDNNFQNTRFTMFVPASNQSDLYKSARIAPVSLTY 503

  Fly   936 HCYCVPSLAASISLS------TN--------RPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETI 986
            ...|:.:...:|:|.      ||        |.|::      :..:|::|.     .||.:.:..
plant   504 FHACLENGNYTINLDFAEIRFTNDENYNRLGRRLFD------IYIQEKLVA-----KDFNIMDEA 557

  Fly   987 RNEESQIVLSVCWNGHKHFI---VQTTGEGNFRFE-----GPPFASIQE---------------- 1027
            :..::.|:..:......||:   :...|:|..|..     ||..::|..
plant   558 KGAQTPIIKPLTAYVTNHFLTIRLSWAGKGTTRIPTRGVYGPIISAISIVSDSKPCERPKTGMSP 622

  Fly  1028 ------------LIM--------------------HQYHSELPVTVKSGAILRRPVCRERWELSN 1060
                        ||:                    ..|..|||    ||....|.:     :.:.
plant   623 GAYIAIGIGAPCLIIFILGFLWICGCLPRCGRQRKDPYEEELP----SGTFTLRQI-----KFAT 678

  Fly  1061 DDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQ-KRKFLQEGRILKQYDHPNIVKL 1124
            ||.....:||.|.||.|:|..|...:: ||||  :::....| .|:||.|...:....|||:|||
plant   679 DDFNPTNKIGEGGFGAVFKGVLADGRV-VAVK--QLSSKSRQGNREFLNEIGAISCLQHPNLVKL 740

  Fly  1125 IGICVQKQPIMIVMELVLGGSLLTYL---RKNSNGLTTRQQMGMCRDAAAGMRYLESKN---CIH 1183
            .|.||::..:::..|.:...||.:.|   :.....:....:..:|...|.|:.:|..::   .:|
plant   741 HGFCVERAQLLLAYEYMENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESPLKFVH 805

  Fly  1184 RDLAARNCLVDLEHSVKISDFGMSR--EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSY 1246
            ||:.|.|.|:|.:.:.||||||::|  |||:..:|..:.. .:.:.|||...:|..|...||:|:
plant   806 RDIKATNILLDKDLTPKISDFGLARLDEEEKTHISTKVAG-TIGYMAPEYALWGYLTFKADVYSF 869

  Fly  1247 GILMWEIFSKGDTPYSGMTNSR-------------ARERIDTGY---------RMPTPKSTPEEM 1289
            |:|:.||       .:|:|||.             |.|.:::|:         |....:...|.:
plant   870 GVLVLEI-------VAGITNSNFMGAGDSVCLLEFANECVESGHLMQVVDERLRPEVDRKEAEAV 927

  Fly  1290 YRLMLQCWAADAESRPHFDEIYNVVDAL 1317
            .::.|.|.:|....||...|:..:::.|
plant   928 IKVALVCSSASPTDRPLMSEVVAMLEGL 955

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.