DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and AT5G49470

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_974914.2	Gene:	AT5G49470 / 835007	AraportID:	AT5G49470	Length:	831	Species:	Arabidopsis thaliana

Alignment Length:	903	Identity:	181/903 - (20%)
Similarity:	292/903 - (32%)	Gaps:	336/903 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   641 LKRTLQPSDD----VNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSE----CRSSKD------- 690
            :::|..|:::    :..:|.::| |::.........::.|:.|.|:|.    .|:|.|
plant     1 MEKTTPPAEELLKKIRELEESQE-HLKREMSRLKVSAEMKQRSHSASPQRPVRRNSNDGTPMWRK 64

  Fly   691 --------------TSHSK--------KRSLSFSQKSISNIFSNLKE------------------ 715
                          .||:|        :.:..|:.|...||..::.:
plant    65 TGAASFRHASPLRKESHAKVAGGGGEGQSAGKFTDKQYLNILQSMAQAVHVFDLNGQIIFWNSMA 129

  Fly   716 -----FSKSPLVRMGKNHILNEEQDAKRTQPSQHHHSSGSD------------------------ 751
                 ||.|..:......||.:.|||...|......|||..
plant   130 EKLYGFSASEALGKDPIDILVDVQDASVAQNITRRCSSGESWTGEFPVKNKAGERFSVVTTMSPS 194

  Fly   752 -----------CPTNSSSSSSNNNNNNKNTSSNSNHSASQSTIITSTITTTITTTTTTTPSKE-- 803
                       |.||.|:...:...:...|........|.|. :||::.:.:     ...|||
plant   195 YDDDGCLIGIICITNDSALFQDPRGSPAKTRRGQEGETSFSR-VTSSVASKL-----GLDSKEAV 253

  Fly   804 ------NSRLKFKVPKIQKKSKAIRNTFRSKL-------LNFQLKRSKPCKQCTKRRRIHPS-KS 854
                  :|:...:|....|.|..:.|..:||:       .|.:......          |.| :.
plant   254 VSKLGLDSQQPIQVAIASKISDLVGNKVKSKMRAGDNNAANLEGGSGDS----------HQSDQG 308

  Fly   855 VFDFAKEFEVEQPAGSAADEQFCNCPPAG---QKPV--------KPSVQISGHKDHPFESSSGEL 908
            .||.|.....|..|.|.||      .|.|   |.|.        |.|.:       ||..||.|.
plant   309 FFDAAFADRREDAATSGAD------TPRGDFIQSPFGVFLRSDEKASTK-------PFRDSSDES 360

  Fly   909 DENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWF------------ 961
            |.||                          .||....|.:         |||.
plant   361 DGNS--------------------------VVPKTLTSKA---------EEWMVKKGLSWPWKGN 390

  Fly   962 ----------HGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTTGEGNFR 1016
                      |.|.|                  .:|||:           .|....|:....:.:
plant   391 EREGLEGRRSHSVWP------------------WVRNEQ-----------QKQQAYQSNSNHSVK 426

  Fly  1017 FEGPPFASIQELI---MHQYHSELPVT---------VKSGAILRR----PVCRERWELSNDDVVL 1065
            .|.....||:...   |..:.|.:.|.         ..|.:::.:    ..|.: :|:..:|:.:
plant   427 SESQACESIKASSNEPMGYWSSSVNVNSTSSSSSCGSTSSSVMNKVDMDSDCLD-YEILWEDLTI 490

  Fly  1066 LERIGRGNFGDVYKAKLKSTKLDVAVKT-CRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICV 1129
            .|:||:|:.|.||......:  |||||. .:....:|....|.||..::|:..|||::..:|...
plant   491 GEQIGQGSCGTVYHGLWFGS--DVAVKVFSKQEYSEEIITSFRQEVSLMKRLRHPNVLLFMGAVT 553

  Fly  1130 QKQPIMIVMELVLGGSLLTY-----------LRKNSNGLTTRQQMGM------CRDA-------- 1169
            ..|.:.||.|.:....|:|.           ||..::.|..:....:      ||..
plant   554 SPQRLCIVTEFLPRFGLITLANITLPFVLFELRGQNSDLPYQITFAVEVSSVCCRGTRQNWIGGD 618

  Fly  1170 ---------------------------------------AAGMRYLESKNC----IHRDLAARNC 1191
                                                   |.||.||.  :|    |||||.:.|.
plant   619 VSIWPRIFYLAYYSLDSLIQLLYLVYNMLHIFLTYFFAQARGMNYLH--HCTPPIIHRDLKSSNL 681

  Fly  1192 LVDLEHSVKISDFGMSR-EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFS 1255
            |||...:||::|||:|| :.|.|:.:...:..| :|.|||.|.........||:|:|:::||:.:
plant   682 LVDKNWTVKVADFGLSRIKHETYLTTKTGRGTP-QWMAPEVLRNEAADEKSDVYSFGVILWELVT 745

  Fly  1256 KGDTPYSGMTNSRARERIDTGY---RMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
            : ..|:..:...:....:  |:   |:..||:...:...||..||.::.:.||.|.||
plant   746 E-KIPWESLNAMQVIGAV--GFMNQRLEVPKNVDPQWISLMESCWHSEPQDRPSFQEI 800

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	16/110 (15%)
		TyrKc	1063..1311	CDD:197581	82/321 (26%)
		PTKc_Fes_like	1067..1315	CDD:270637	82/317 (26%)
AT5G49470	NP_974914.2	PAS	100..210	CDD:279347	17/109 (16%)
		PAS	109..210	CDD:238075	14/100 (14%)
		Pkinase_Tyr	488..804	CDD:285015	82/321 (26%)
		STKc_MAP3K-like	494..804	CDD:270901	81/315 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000