DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and AT3G58760

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001325814.1	Gene:	AT3G58760 / 825045	AraportID:	AT3G58760	Length:	534	Species:	Arabidopsis thaliana

Alignment Length:	474	Identity:	117/474 - (24%)
Similarity:	192/474 - (40%)	Gaps:	83/474 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   885 KPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISL 949
            ||..|:....|.:        ..|...|...||...|:||   ||:.:         :..|.|..
plant    67 KPKSPARFKLGRQ--------SSLAPESRTPIDTLTEDED---DDLAA---------AATAGIGD 111

  Fly   950 STNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSV--CWNGHKHFIVQTTGE 1012
            .|.|.:|        |..|..:..:|...|.......|:.:::..|.|  | .|....:......
plant   112 PTIRLMY--------LANEGDIDGINKMLDSGTNVDYRDIDARTALHVAAC-QGRTDVVELLLSR 167

  Fly  1013 G-----NFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLE----- 1067
            |     ..|:...|.|   :.:.::.|..:.:..|.||   :|.......|::.:|...|
plant   168 GAKVDTKDRWGSTPLA---DAVYYKNHDVIKLLEKHGA---KPTIAPMHVLTDKEVPEYEIHPTE 226

  Fly  1068 -------RIGRGNFGDVYKAKLKSTKLDVAVKTC--RMTLPDEQKRKFLQEGRILKQYDHPNIVK 1123
                   :|.:|.|.   ||..:.  :||||||.  .|...:::...|..|..:|::..|||:|:
plant   227 LDFSNSVKISKGTFN---KASWRG--IDVAVKTFGEEMFTDEDKVNAFRDELALLQKIRHPNVVQ 286

  Fly  1124 LIGICVQKQPIMIVMELVLGGSLLTYL-RKNSNGLTTRQQMGMCRDAAAGMRYL---ESKNCIHR 1184
            .:|...|..|:|||.|.:..|.|..|| ||..  |.....:....:.|.||.||   :.:..||.
plant   287 FLGAVTQSTPMMIVTEYLPKGDLRQYLDRKGP--LMPAHAVKFALEIARGMNYLHEHKPEAIIHC 349

  Fly  1185 DLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQ-IPV--------KWTAPEALNFGKYTSL 1240
            ||...|.|.|....:|::|||:|:   ..:|...:|: .||        ::.|||.....:|.:.
plant   350 DLEPPNILRDDSGHLKVADFGVSK---LLVVKKTVKKDRPVVTCLDSSWRYMAPEVYRNEEYDTK 411

  Fly  1241 CDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMP---TPKSTPEEMYRLMLQCWAADAE 1302
            .||:|:.:::.|:. :|..|:..:.:....:......|.|   ..||.|..:..|:..||..:|.
plant   412 VDVFSFALILQEMI-EGCEPFHEIEDREVPKAYIEDERPPFNAPTKSYPFGLQELIQDCWDKEAS 475

  Fly  1303 SRPHFDEIYNVVDALILRL 1321
            .||.|..|.:.::.:..|:
plant   476 KRPTFRVIISTLELISDRI 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	16/92 (17%)
		TyrKc	1063..1311	CDD:197581	78/277 (28%)
		PTKc_Fes_like	1067..1315	CDD:270637	78/277 (28%)
AT3G58760	NP_001325814.1	Ank_2	116..206	CDD:403870	19/104 (18%)
		ANK repeat	116..142	CDD:293786	5/33 (15%)
		ANK repeat	144..175	CDD:293786	5/31 (16%)
		ANK repeat	177..206	CDD:293786	7/34 (21%)
		STKc_MAP3K-like	235..487	CDD:270901	77/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910