DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and AT3G22750

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_566716.1	Gene:	AT3G22750 / 821846	AraportID:	AT3G22750	Length:	378	Species:	Arabidopsis thaliana

Alignment Length:	310	Identity:	86/310 - (27%)
Similarity:	149/310 - (48%)	Gaps:	42/310 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1041 VKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVK----------TCR 1095
            |.|.:|.:.|..:|.||:....:.:...|.||.:|.|||......  |||||          |..
plant    52 VWSRSIEKHPKPKEEWEIELAKLEMRNVIARGAYGIVYKGIYDGQ--DVAVKVLDWGEDGYATTA 114

  Fly  1096 MTLPDEQKRKFLQEGRILKQYDHPNIVKLIGI-----------------CVQKQPIMIVMELVLG 1143
            .|  ...:..|.||..:..:.||||:.:.:|.                 .:.::...:|:|.:.|
plant   115 ET--SALRASFRQEVAVWHKLDHPNVTRFVGASMGTANLKIPSSAETENSLPQRACCVVVEYIPG 177

  Fly  1144 GSLLTYL-RKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMS 1207
            |:|..|| |.....|..:..:.:..|.:.|:.||.|:..:|||:...|.|:|.:.::||:|||::
plant   178 GTLKQYLFRNRRKKLAFKVVVQLALDLSRGLSYLHSERIVHRDVKTENMLLDYQRNLKIADFGVA 242

  Fly  1208 REEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPY-----SGMTNS 1267
            |.|.:.......:...:.:.|||.|:...|...|||:|:||.:|||:. .|.||     :.::::
plant   243 RVEAQNPKDMTGETGTLGYMAPEVLDGKPYNRRCDVYSFGICLWEIYC-CDMPYPDLSFADVSSA 306

  Fly  1268 RARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
            ..|:.:    |...|:..|..:..:|.:||.|:.|.||..:|:.::::|:
plant   307 VVRQNL----RPDIPRCCPTALATIMKRCWEANPEKRPEMEEVVSLLEAV 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	78/280 (28%)
		PTKc_Fes_like	1067..1315	CDD:270637	78/280 (28%)
AT3G22750	NP_566716.1	Pkinase_Tyr	74..349	CDD:285015	78/283 (28%)
AT3G22750	NP_566716.1	STKc_MAP3K-like	80..349	CDD:270901	78/277 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810