DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and AT3G06630

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001326620.1	Gene:	AT3G06630 / 819842	AraportID:	AT3G06630	Length:	698	Species:	Arabidopsis thaliana

Alignment Length:	928	Identity:	195/928 - (21%)
Similarity:	339/928 - (36%)	Gaps:	274/928 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   411 LEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLTLLRGRGRHFKRKSTPQPATPMTRSRQ 475
            :|:..::.....||.:.         ::.:.|.|..:.|.||            ||:.|:...|
plant     1 MEEELLKKMLELEQSQE---------LLKQEMSRLKLSTELR------------QPSHPVLPRR- 43

  Fly   476 GRFNKLQPRSQSLGSLSVIRDGNGPSPARY--EPITNHRLRQAASVHYLGEEIATSSTNPPDL-T 537
                   |..:..||::     :.|||.::  :...|.....|.|||.|            || |
plant    44 -------PLRRIQGSMN-----SNPSPGKFTDKQYLNILQSLAQSVHVL------------DLNT 84

  Fly   538 RLRRTQCSMLCLGEDEEPVVL--ASPAPLTQLTAAVLTNTNNNHIYAD-----LELDKKKDTSPS 595
            |                 ::.  |....|...:||.:...|..|:..|     ..|:..:..:..
plant    85 R-----------------IIFWNAMSEKLYGYSAAEVVGRNPVHVIVDDQNAAFALNVARRCANG 132

  Fly   596 PECKGE-QIQPKKEQIRIEINQTAP----QNSIDAHLDRIDELNRVLDDRLK-RTLQPSDDVNAI 654
            ....|| .::.|..:|...:...:|    ..::...:....::...|:.||. ..|:|.:
plant   133 ESWTGEFPVKTKSGKIFSAVTTCSPFYDDNGTVVGIISITSDIAPYLNPRLSLPRLKPQE----- 192

  Fly   655 ESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNIFSNLKEFSKS 719
                    ..|||..|        |..:...:...|:....:.|::....|:::..|| |..||
plant   193 --------PERKLGLD--------SKGAVISKPGLDSDQPIQVSIASKISSLASKLSN-KVRSK- 239

  Fly   720 PLVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNSNHSASQSTII 784
              :|.|.|....:.           |||        ......:..:::::.:::|..|..:...|
plant   240 --MRAGDNSACGDS-----------HHS--------DHDVFGDTLSDHRDDAASSGASTPRGDFI 283

  Fly   785 TST--ITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKR--SKPCKQCTK 845
            .|.  :.|.......:.|||::|          .:..||.....||...:.:|:  |:|.|...:
plant   284 QSPFGVFTCYDDKFPSKPSKDSS----------DRKPAIHKVPTSKAEEWMVKKGLSRPWKGNEQ 338

  Fly   846 R-RRIHPSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELD 909
            . .|:.|:.||:.:. |.|.|:      |:.....|.||.|.               ||...|.:
plant   339 EGSRVRPTHSVWSWV-ENEQEK------DKYHQIYPSAGVKS---------------ESHGSESN 381

  Fly   910 ENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLL 974
            :.:|.:..|......:|:.             :.:||...||:|.:.::               :
plant   382 KPTDDEASNMWSSSINANS-------------TNSASSCGSTSRSVMDK---------------V 418

  Fly   975 NNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTTGEGNFRFEGPPFASIQELIMHQYHSELPV 1039
            :.|.|.|..|            :.|
plant   419 DIDSDPLEHE------------ILW---------------------------------------- 431

  Fly  1040 TVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKT-CRMTLPDEQK 1103
                                 ||:.:.|:||||:.|.||......:  |||||. .:....:...
plant   432 ---------------------DDLTIGEQIGRGSCGTVYHGIWFGS--DVAVKVFSKQEYSESVI 473

  Fly  1104 RKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRD 1168
            :.|.:|..::|:..|||::..:|.....|.:.||.|.|..|||...|:::.:.|..|:::.|..|
plant   474 KSFEKEVSLMKRLRHPNVLLFMGAVTSPQRLCIVSEFVPRGSLFRLLQRSMSKLDWRRRINMALD 538

  Fly  1169 AAAGMRYLE--SKNCIHRDLAARNCLVDLEHSVKISDFGMSR-EEEEYIVSDGMKQIPVKWTAPE 1230
            .|.||.||.  |...|||||.:.|.|||...:||::|||:|| :.:.|:.|...|..| :|.|||
plant   539 IARGMNYLHCCSPPIIHRDLKSSNLLVDRNWTVKVADFGLSRIKHQTYLTSKSGKGTP-QWMAPE 602

  Fly  1231 ALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGY---RMPTPKSTPEEMYRL 1292
            .|.........|::|:|:::||:.:: ..|:..:.:.:....:  |:   |:..||.|..:...|
plant   603 VLRNESADEKSDIYSFGVVLWELATE-KIPWENLNSMQVIGAV--GFMNQRLEIPKDTDPDWISL 664

  Fly  1293 MLQCWAADAESRPHFDEI 1310
            :..||.:|.:.||.|.|:
plant   665 IESCWHSDTKLRPTFQEL 682

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	6/85 (7%)
		TyrKc	1063..1311	CDD:197581	83/255 (33%)
		PTKc_Fes_like	1067..1315	CDD:270637	83/251 (33%)
AT3G06630	NP_001326620.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910