Protein Alignment FER and Frk

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_077344.1
• Gene: Frk / 79209
• RGDID: 621423
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 390
• Identity: 138/390 - (35%)
• Similarity: 218/390 - (55%)
• Gaps: 37/390 - (9%)

  Fly   949 LSTNRPLYEEEWFHGVLPREEVVRLL----NNDGDFLVRETIRNEESQIVLSVCWNG-HKHFIVQ 1008
            ::.:|.|..|.||.|.:.|.:..:.|    |..|.||:||: .:::....|||...| .||:.::
  Rat   106 VAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRES-ESQKGDFSLSVLDEGVVKHYRIR 169

  Fly  1009 TTGEGNFRF-EGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCR--------------ERWEL 1058
            ...||.|.. ....|:::.|.:.:...:...:.||    |.:|..:              ::||:
  Rat   170 RLDEGGFFLTRRKTFSTLNEFVNYYTTTSDGLCVK----LEKPCLKIQVPTPFDLSYKTVDQWEI 230

  Fly  1059 SNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVK 1123
            ..:.:.||:|:|.|.||:|::....:| ..|||||.:....|  ...||:|.:|:|...||.:::
  Rat   231 DRNSIQLLKRLGSGQFGEVWEGLWNNT-TPVAVKTLKPGSMD--PNDFLREAQIMKSLRHPKLIQ 292

  Fly  1124 LIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTR--QQMGMCRDAAAGMRYLESKNCIHRDL 1186
            |..:|..:.||.|:.||:..|||..|| :|..|...|  ||:.|....|:||.||||:|.|||||
  Rat   293 LYAVCTLEDPIYIITELMRHGSLQEYL-QNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDL 356

  Fly  1187 AARNCLVDLEHSV-KISDFGMSR----EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSY 1246
            ||||.||. ||:: |::|||::|    :.|:...|....::|||||||||:...|::...||||:
  Rat   357 AARNVLVG-EHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSF 420

  Fly  1247 GILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIY 1311
            |||::||.:.|..||||||.::....:...||:|.|.:.||:.|.:|::||..:.:.||.|:.::
  Rat   421 GILLYEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETLH 485

  Fly  1312  1311
              Rat   486  485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	25/91 (27%)
		TyrKc	1063..1311	CDD:197581	107/254 (42%)
		PTKc_Fes_like	1067..1315	CDD:270637	105/252 (42%)
Frk	NP_077344.1	SH3_Src_like	48..105	CDD:212779
		SH2_Src_Frk	113..208	CDD:199831	26/99 (26%)
		PTKc_Frk_like	226..495	CDD:270653	109/265 (41%)
		Pkinase_Tyr	235..488	CDD:285015	107/256 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910