| Sequence 1: | NP_524288.3 | Gene: | FER / 41118 | FlyBaseID: | FBgn0000723 | Length: | 1325 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_077060.2 | Gene: | Fgfr1 / 79114 | RGDID: | 620713 | Length: | 822 | Species: | Rattus norvegicus |
| Alignment Length: | 762 | Identity: | 177/762 - (23%) |
|---|---|---|---|
| Similarity: | 274/762 - (35%) | Gaps: | 230/762 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 721 LVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNSNHSASQSTIIT 785
Fly 786 STITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCKQCTKRRRIH 850
Fly 851 PSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQ-----------KPVKPSVQISGHK------- 897
Fly 898 ---DHPFESSSGE---LDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAA------SISLS 950
Fly 951 TN---------RPLYEEEWFHGV-----------LP---------------REEVVRLLN----N 976
Fly 977 DGDF-----------------LVRETIRNEESQIVLS-----------------VCWNGHKHFIV 1007
Fly 1008 QTTGEGNFRFEGPPFASIQELIMHQYHSELP----VTV--------KSGAILRRPVCRE------ 1054
Fly 1055 -------------RWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLD-------VAVKTCRMTLP 1099
Fly 1100 DEQKRKFLQEGRILKQY-DHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKN---------- 1153
Fly 1154 -----SNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSRE--EE 1211
Fly 1212 EYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTG 1276
Fly 1277 YRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDN 1323 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FER | NP_524288.3 | F-BAR_Fes_Fer | 7..243 | CDD:153341 | |
| SH2_Fps_family | 953..1039 | CDD:198224 | 20/153 (13%) | ||
| PTKc_Fes_like | 1067..1315 | CDD:270637 | 91/272 (33%) | ||
| Fgfr1 | NP_077060.2 | IgI_1_FGFR | 25..118 | CDD:409362 | 13/66 (20%) |
| Ig strand A | 25..28 | CDD:409362 | |||
| Ig strand A' | 40..46 | CDD:409362 | |||
| Ig strand B | 49..59 | CDD:409362 | |||
| Ig strand C | 63..68 | CDD:409362 | |||
| Ig strand C' | 71..73 | CDD:409362 | 177/762 (23%) | ||
| Ig strand D | 78..82 | CDD:409362 | 0/3 (0%) | ||
| Ig strand E | 85..90 | CDD:409362 | 1/4 (25%) | ||
| Ig strand F | 96..105 | CDD:409362 | 3/8 (38%) | ||
| Ig strand G | 108..118 | CDD:409362 | 2/9 (22%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 120..162 | 9/72 (13%) | |||
| IgI_2_FGFR | 153..247 | CDD:409443 | 20/102 (20%) | ||
| Ig strand A | 153..156 | CDD:409443 | 1/5 (20%) | ||
| Heparin-binding | 160..177 | 4/16 (25%) | |||
| Ig strand A' | 164..169 | CDD:409443 | 1/4 (25%) | ||
| Ig strand B | 173..181 | CDD:409443 | 2/7 (29%) | ||
| Ig strand C | 187..192 | CDD:409443 | 0/4 (0%) | ||
| Ig strand C' | 195..197 | CDD:409443 | 1/1 (100%) | ||
| Ig strand D | 206..209 | CDD:409443 | 1/2 (50%) | ||
| Ig strand E | 213..218 | CDD:409443 | 0/4 (0%) | ||
| Ig strand F | 227..234 | CDD:409443 | 0/6 (0%) | ||
| Ig strand G | 237..247 | CDD:409443 | 1/15 (7%) | ||
| Ig | 255..359 | CDD:472250 | 14/103 (14%) | ||
| Ig strand B | 273..277 | CDD:409444 | 0/3 (0%) | ||
| Ig strand C | 286..290 | CDD:409444 | 0/3 (0%) | ||
| Ig strand E | 324..328 | CDD:409444 | 2/3 (67%) | ||
| Ig strand F | 338..343 | CDD:409444 | 0/4 (0%) | ||
| Ig strand G | 351..354 | CDD:409444 | 0/2 (0%) | ||
| PTKc_FGFR1 | 464..765 | CDD:270678 | 100/300 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 770..822 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||