DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and Map3k20

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_075544.1	Gene:	Map3k20 / 65964	MGIID:	2443258	Length:	802	Species:	Mus musculus

Alignment Length:	266	Identity:	84/266 - (31%)
Similarity:	131/266 - (49%)	Gaps:	17/266 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1057 ELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNI 1121
            ::..||:...|..|.|:||.||:||..|...:||||         :..|..:|..||....|.||
Mouse    10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVK---------KLLKIEKEAEILSVLSHRNI 65

  Fly  1122 VKLIGICVQKQPIMIVMELVLGGSLLTYLRKN-SNGLTTRQQMGMCRDAAAGMRYLESK---NCI 1182
            ::..|:.::.....||.|....|||..|:..| |..:.....|....|.|.||.||..:   ..|
Mouse    66 IQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVI 130

  Fly  1183 HRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYG 1247
            ||||.:||.::..:..:||.|||.||..........:...|  |.|||.:.....:..||.:|||
Mouse   131 HRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP--WMAPEVIQSLPVSETCDTYSYG 193

  Fly  1248 ILMWEIFSKGDTPYSGMTNSR-ARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIY 1311
            :::||:.:: :.|:.|:...: |...::...|:..|.|.|.....|:.|||.|||:.||.|.:|.
Mouse   194 VVLWEMLTR-EVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQII 257

  Fly  1312 NVVDAL 1317
            ::::::
Mouse   258 SILESM 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	81/252 (32%)
		PTKc_Fes_like	1067..1315	CDD:270637	82/252 (33%)
Map3k20	NP_075544.1	STKc_MLTK	22..263	CDD:270962	81/252 (32%)
		Leucine-zipper	287..308
		SAM_MLTK	338..408	CDD:188928
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	624..802
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900