Protein Alignment FER and Pik3r3

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_071549.2
• Gene: Pik3r3 / 60664
• RGDID: 621042
• Length: 461
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 69/312 - (22%)
• Similarity: 108/312 - (34%)
• Gaps: 115/312 - (36%)

  Fly   863 EVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSAS 927
            |::.||          .||...|||..:| .:|.||
  Rat    31 EMDPPA----------LPPKPPKPVTSAV-TNGMKD----------------------------- 55

  Fly   928 DDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNN--DGDFLVRETIRNEE 990
                     |:        :||.      :.||:.|.:.||||...|.:  ||.||||:.....:
  Rat    56 ---------CF--------VSLQ------DAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQ 97

  Fly   991 SQIVLSVCWNGHKHFIVQTTGEGNFRFEGP-PFASIQELIMHQYHSEL-PVTVKSGAILRRPVCR 1053
            ....|::...|:...|.....:|.:.|..| .|.|:.|||.|.:|..| ....|....|..||.|
  Rat    98 GDYTLTLRKGGNNKLIKIYHRDGKYGFSEPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSR 162

  Fly  1054 -ERWELSNDDVVLLERIGRG--NFGDVYKAK-------------------LKSTKLDVAVKTCRM 1096
             ::.:|..:|.:  :.:|:.  .|...|:.|                   :|.|.::...:|.::
  Rat   163 YQQDQLVKEDNI--DAVGKNLQEFHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKI 225

  Fly  1097 ------TLPDEQK---RKFLQEG------RILKQYD---------HPNIVKL 1124
                  |.....|   .:|.:||      ||:..||         |.:.|:|
  Rat   226 FEEQCHTQEQHSKDYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKVRL 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	28/89 (31%)
		TyrKc	1063..1311	CDD:197581	19/107 (18%)
		PTKc_Fes_like	1067..1315	CDD:270637	19/103 (18%)
Pik3r3	NP_071549.2	SH2_nSH2_p85_like	59..167	CDD:198195	35/113 (31%)
		iSH2_PI3K_IA_R	172..332	CDD:355389	20/108 (19%)
		SH2_cSH2_p85_like	351..454	CDD:198184

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910