Protein Alignment FER and fgfr3

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_021336328.1
• Gene: fgfr3 / 58129
• ZFINID: ZDB-GENE-000816-1
• Length: 821
• Species: Danio rerio
• Alignment Length: 402
• Identity: 119/402 - (29%)
• Similarity: 174/402 - (43%)
• Gaps: 98/402 - (24%)

  Fly   942 SLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFI 1006
            ||.::.|:::|.||.            .:.||.::|
Zfish   433 SLESNSSMNSNTPLV------------RIARLSSSD----------------------------- 456

  Fly  1007 VQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGR 1071
                        ||...::.||       |||...|             ||.:...:.|.:.:|.
Zfish   457 ------------GPMLPNVSEL-------ELPSDPK-------------WEFTRTKLTLGKPLGE 489

  Fly  1072 GNFGDVYKA------KLKSTK-LDVAVKTCRMTLPDEQKRKFLQEGRILKQY-DHPNIVKLIGIC 1128
            |.||.|..|      |.|..| |.||||..:....|:.....:.|..::|.. .|.||:.|:|.|
Zfish   490 GCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGAC 554

  Fly  1129 VQKQPIMIVMELVLGGSLLTYLRKN---------------SNGLTTRQQMGMCRDAAAGMRYLES 1178
            .|..|:.:::|....|:|..|||..               :..||.:..:......|.||.||.|
Zfish   555 TQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLAS 619

  Fly  1179 KNCIHRDLAARNCLVDLEHSVKISDFGMSREEE--EYIVSDGMKQIPVKWTAPEALNFGKYTSLC 1241
            |.||||||||||.||..::.:||:|||::|:..  :|.......::||||.|||||....||...
Zfish   620 KKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQS 684

  Fly  1242 DVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPH 1306
            ||||||:|:||||:.|.:||.|:......:.:..|:||..|.:...|:|.:|.:||.|....||.
Zfish   685 DVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPT 749

  Fly  1307 FDEIYNVVDALI 1318
            |.::....|.::
Zfish   750 FRQLVEDHDRVL 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	11/85 (13%)
		TyrKc	1063..1311	CDD:197581	99/272 (36%)
		PTKc_Fes_like	1067..1315	CDD:270637	98/272 (36%)
fgfr3	XP_021336328.1	IGc2	67..121	CDD:197706
		Ig2_FGFR	173..257	CDD:143265
		Ig3_FGFR-2	280..369	CDD:143266
		PTKc_FGFR3	468..801	CDD:173652	105/307 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900