Protein Alignment FER and map3k10

DIOPT Version :10

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_689424.4
• Gene: map3k10 / 560932
• ZFINID: ZDB-GENE-050419-112
• Length: 1062
• Species: Danio rerio
• Alignment Length: 270
• Identity: 85/270 - (31%)
• Similarity: 127/270 - (47%)
• Gaps: 40/270 - (14%)

  Fly  1065 LLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQ----KRKFLQEGRILKQYDHPNIVKLI 1125
            |.|.||.|.||.|||...::.  :||||..|.. |||.    .....||.|:.....|.||:.|.
Zfish   167 LEEVIGAGGFGKVYKGVWRAE--EVAVKAARQD-PDEDISATAENVRQEARLFWMLRHRNIIALR 228

  Fly  1126 GICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKN---CIHRDLA 1187
            |:|:::..:.:|||...||:|...|.  ...:..|..:......|.||.||.::.   .|||||.
Zfish   229 GVCLREPNLCLVMEYARGGALNRALA--GKKVPPRVLVNWAVQIATGMDYLHNQTFVPIIHRDLK 291

  Fly  1188 ARNCLV-------DLE-HSVKISDFGMSRE--EEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCD 1242
            :.|.|:       ||. .::||:|||::||  ....:.:.|    ...|.|||.:....::...|
Zfish   292 SSNILILEPVERDDLSGKTLKITDFGLAREWHRTTKMSAAG----TYAWMAPEVIKLSLFSKSSD 352

  Fly  1243 VWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGY-------RMPTPKSTPEEMYRLMLQCWAAD 1300
            |||:|:|:||:.: |:.||      |..:.:...|       .:|.|.:.||...:|:.:||..:
Zfish   353 VWSFGVLLWELLT-GEVPY------REIDALAVAYGVAMNKLTLPIPSTCPEAFAQLLGECWCPN 410

  Fly  1301 AESRPHFDEI 1310
            ...||.|..|
Zfish   411 PRGRPAFGSI 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		PTKc_Fes_like	1067..1315	CDD:270637	84/268 (31%)
map3k10	XP_689424.4	SH3_MLK1-3	81..138	CDD:212992
		STKc_MLK2	170..427	CDD:271050	83/267 (31%)