DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FER and zak

DIOPT Version :9

Sequence 1:NP_524288.3 Gene:FER / 41118 FlyBaseID:FBgn0000723 Length:1325 Species:Drosophila melanogaster
Sequence 2:NP_001314869.1 Gene:zak / 559247 ZFINID:ZDB-GENE-070912-386 Length:789 Species:Danio rerio


Alignment Length:266 Identity:84/266 - (31%)
Similarity:131/266 - (49%) Gaps:17/266 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly  1057 ELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNI 1121
            ::..||:...|..|.|:||.||:|:..|...:||||         :..|..:|..||....|.||
Zfish    10 QIKFDDIHFYENCGGGSFGSVYRARWLSQDREVAVK---------KLLKIEKEAEILSVLSHRNI 65

  Fly  1122 VKLIGICVQKQPIMIVMELVLGGSLLTYLRK-NSNGLTTRQQMGMCRDAAAGMRYLESK---NCI 1182
            :|..|..::.....||.|...||||..||.. :|..::.:|.|....|.|.||.||.|:   ..|
Zfish    66 IKFYGAILEAPNYGIVTEYASGGSLFDYLSSDDSEDISMQQIMTWAMDIAKGMHYLHSEAPVKVI 130

  Fly  1183 HRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYG 1247
            ||||.:||.::..:..:||.|||.|:..........:...|  |.|||.:.....:..||.:|||
Zfish   131 HRDLKSRNVVLSSDSVLKICDFGASKFHSHTTHMSLVGTFP--WMAPEVIQSLPVSETCDTFSYG 193

  Fly  1248 ILMWEIFSKGDTPYSGMTNSR-ARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIY 1311
            :::||:.:: :.|:.|:...: |...::...|:..|.|.|.....||..|||.:.:.||.|..|.
Zfish   194 VVLWEMLTQ-EIPFKGLEGLQVAWLVVEKHERLTIPSSCPASFACLMRSCWATEPKERPLFKHIL 257

  Fly  1312 NVVDAL 1317
            :.::::
Zfish   258 STLESM 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FERNP_524288.3 F-BAR_Fes_Fer 7..243 CDD:153341
SH2_Fps_family 953..1039 CDD:198224
TyrKc 1063..1311 CDD:197581 81/252 (32%)
PTKc_Fes_like 1067..1315 CDD:270637 82/252 (33%)
zakNP_001314869.1 STYKc 16..260 CDD:214568 82/255 (32%)
PKc_like 22..263 CDD:304357 81/252 (32%)
SAM_MLTK 338..405 CDD:188928
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100013
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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