DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and grapb

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001025251.2	Gene:	grapb / 555184	ZFINID:	ZDB-GENE-050913-4	Length:	214	Species:	Danio rerio

Alignment Length:	187	Identity:	42/187 - (22%)
Similarity:	81/187 - (43%)	Gaps:	31/187 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   907 ELDENSDR-----DIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLP 966
            |.||.|.:     .:.|.:::.:..:.::|..:.:   ||....::     ||   ..||.|.:.
Zfish    13 ECDELSFQKGEILKVTNMDDDPNWYTAELLGRRGY---VPKNYINV-----RP---HTWFVGGIS 66

  Fly   967 REEVVRLLN--NDGDFLVRETIRNEESQIVLSVCWNGH-KHFIVQTTGEGNFRFEGPPFASIQEL 1028
            |:.....|.  ..|.||:||: .:...:..:||.:..| :||.|...|.|.:......|:|:.:|
Zfish    67 RQAAENRLRPLECGAFLIRES-ESTPGEFSVSVSYGDHVQHFKVLKDGLGQYFIWDEVFSSLNQL 130

  Fly  1029 IMHQYHSELPVTVKSGAILRRP---VCRER-----WELSNDDVVLLERIGRGNFGDV 1077
            :  .::....:..:....||.|   :.|.|     ::.:::.|..| |..||:..|:
Zfish   131 V--DFYRINSIAKERTVFLREPEGSLARPRHAHAIFDFTSNHVTHL-RFLRGDVIDL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	23/88 (26%)
		TyrKc	1063..1311	CDD:197581	6/15 (40%)
		PTKc_Fes_like	1067..1315	CDD:270637	4/11 (36%)
grapb	NP_001025251.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000