DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and ptk7a

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001018501.1	Gene:	ptk7a / 553690	ZFINID:	ZDB-GENE-050522-216	Length:	231	Species:	Danio rerio

Alignment Length:	189	Identity:	43/189 - (22%)
Similarity:	65/189 - (34%)	Gaps:	57/189 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   470 MTRSRQGRFNKLQPRSQSL--GSLSVIR-DGNGPSPARY------EPITN--HRLRQAASVHYLG 523
            |.::....|.| .|:||..  |..:::| :.|.|....|      ||:||  .|.....::.:..
Zfish    30 MAQAASFYFTK-APKSQDALHGRSAMLRCEVNDPQGVSYAWIQNGEPVTNSERRFLDGGNLKFTA 93

  Fly   524 EEIATSSTNPPDLTRLRRTQC--SMLCLGEDEE--------------PVVLASPAPLTQL--TAA 570
            .:....|.|         .||  |....||:|.              .|.|.||..:.::  ::.
Zfish    94 IDRTLDSGN---------FQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQ 149

  Fly   571 VLTNTNNNHIYADLELDKKKDTSPSPECK----GEQIQPKKEQI-RIEINQTAPQNSID 624
            |:...|             .|..|.|..:    |.||..|..:| ..|.:.|.|..|.|
Zfish   150 VILRCN-------------IDGHPRPTNRWFKDGTQITEKNYKINNKERSLTLPNASPD 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
ptk7a	NP_001018501.1	I-set	37..120	CDD:254352	23/92 (25%)
		Ig	42..122	CDD:299845	21/88 (24%)
		Ig	150..222	CDD:299845	15/59 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910