DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and grapa

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001018409.1	Gene:	grapa / 553596	ZFINID:	ZDB-GENE-050522-347	Length:	214	Species:	Danio rerio

Alignment Length:	117	Identity:	33/117 - (28%)
Similarity:	53/117 - (45%)	Gaps:	15/117 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   916 IDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVV-RLLNND-G 978
            |.|.|::.:..:.:.::.|.:   ||....|:     ||   ..||.|.:.|.... ||...| |
Zfish    27 ITNMEDDPNWYTAEFVNRKGY---VPKNYISL-----RP---HAWFAGRISRHVAENRLHQRDCG 80

  Fly   979 DFLVRETIRNEESQIVLSVCWNGH-KHFIVQTTGEGNFRFEGPPFASIQELI 1029
            .|||||: .:...:..:||.:..| :||.|....||.:......|.|:.:|:
Zfish    81 SFLVRES-ESAPGEFSMSVSYGDHVQHFKVLKDREGYYFVWEEIFPSLNQLV 131

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	26/80 (33%)
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
grapa	NP_001018409.1	SH3	2..55	CDD:302595	6/30 (20%)
		SH2_Grb2_like	56..149	CDD:199828	26/80 (33%)
		SH3_GRB2_like_C	159..211	CDD:212739
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910