DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and Sla2

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001165589.1	Gene:	Sla2 / 499931	RGDID:	1562071	Length:	263	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	59/277 - (21%)
Similarity:	92/277 - (33%)	Gaps:	89/277 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   865 EQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELD------ENSDRDIDNDEEEE 923
            ::|....|:.|..:....|..|.....::|.....|....|.:.|      |.|.|:
  Rat    25 QEPVSIQAERQKVSAVALGSFPAGEQARLSLRVGEPLTIISEDGDWWTVQSEVSGRE-------- 81

  Fly   924 DSASDDVLSMKDHCYCVPSL-AASISLSTNRPLYEEEWFHGVLPREEVVRLL----NNDGDFLVR 983
                          |.:||: .|.:|         ..|.:..|.||:...||    |..|.||:|
  Rat    82 --------------YHIPSVYVAKVS---------HGWLYEGLSREKAEELLLLPGNPGGAFLIR 123

  Fly   984 ETIRNEESQIVLSV------CWNGHKHFIVQTTGEGNFRFEGP--PFASIQELIMHQYHSELPVT 1040
            |: :.......||:      .|:..:|:.:|....| :.:..|  .|.|:..|:.|  :|||...
  Rat   124 ES-QTRRGCYSLSIRLSRPASWDRIRHYRIQRLDNG-WLYISPRLTFPSLHALVEH--YSELADG 184

  Fly  1041 VKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMT-------- 1097
            :  ...||.| |            :|:::|        ....|.|.|.|.|.|..:.
  Rat   185 I--CCALREP-C------------VLQKLG--------PLPGKDTPLPVTVPTSSLNWKKLDRSL 226

  Fly  1098 ----LPDEQKRKFLQEG 1110
                .|...:...|.||
  Rat   227 LCLDAPASGEASLLSEG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	26/97 (27%)
		TyrKc	1063..1311	CDD:197581	12/60 (20%)
		PTKc_Fes_like	1067..1315	CDD:270637	11/56 (20%)
Sla2	NP_001165589.1	SH3	39..92	CDD:302595	13/74 (18%)
Sla2	NP_001165589.1	SH2_SLAP	85..187	CDD:198207	30/116 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910