| Sequence 1: | NP_524288.3 | Gene: | FER / 41118 | FlyBaseID: | FBgn0000723 | Length: | 1325 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002520.2 | Gene: | NTRK1 / 4914 | HGNCID: | 8031 | Length: | 796 | Species: | Homo sapiens |
| Alignment Length: | 479 | Identity: | 133/479 - (27%) |
|---|---|---|---|
| Similarity: | 216/479 - (45%) | Gaps: | 102/479 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 881 PAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLA- 944
Fly 945 -----ASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDG---DF-LVRETIRNEESQIVLSVCWN 1000
Fly 1001 GHKHFIV-------QTTGEGNFRFEGPPFASIQELIMH--QYHSELPVTVKSGAILRRPVCRERW 1056
Fly 1057 ELSNDDVVLLERIGRGNFGDVYKAKL-----KSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQY 1116
Fly 1117 DHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNG----------------LTTRQQMGM 1165
Fly 1166 CRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSRE--EEEYIVSDGMKQIPVKWTA 1228
Fly 1229 PEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLM 1293
Fly 1294 LQCWAADAESRPHFDEIYNVVDAL 1317 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FER | NP_524288.3 | F-BAR_Fes_Fer | 7..243 | CDD:153341 | |
| SH2_Fps_family | 953..1039 | CDD:198224 | 17/98 (17%) | ||
| TyrKc | 1063..1311 | CDD:197581 | 88/270 (33%) | ||
| PTKc_Fes_like | 1067..1315 | CDD:270637 | 86/270 (32%) | ||
| NTRK1 | NP_002520.2 | leucine-rich repeat | 68..92 | CDD:275378 | |
| LRR 1 | 90..113 | ||||
| LRR_8 | 92..150 | CDD:290566 | |||
| leucine-rich repeat | 93..116 | CDD:275378 | |||
| LRR 2 | 116..137 | ||||
| leucine-rich repeat | 117..139 | CDD:275378 | |||
| leucine-rich repeat | 140..152 | CDD:275378 | |||
| TPKR_C2 | 151..192 | CDD:293525 | |||
| Ig_TrkABC_d4 | 195..282 | CDD:143173 | |||
| Ig_TrKABC_d5 | 299..379 | CDD:143172 | 4/15 (27%) | ||
| Interaction with SQSTM1. /evidence=ECO:0000250 | 469..490 | 4/29 (14%) | |||
| PTKc_TrkA | 504..783 | CDD:270674 | 92/293 (31%) | ||
| Pkinase_Tyr | 510..781 | CDD:285015 | 88/273 (32%) | ||
| DXXLL. /evidence=ECO:0000269|PubMed:26446845 | 537..541 | 1/3 (33%) | |||
| DXXLL. /evidence=ECO:0000269|PubMed:26446845 | 607..611 | 0/3 (0%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||