DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and AgaP_AGAP009157

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_001238225.2	Gene:	AgaP_AGAP009157 / 4578386	VectorBaseID:	AGAP009157	Length:	347	Species:	Anopheles gambiae

Alignment Length:	272	Identity:	97/272 - (35%)
Similarity:	152/272 - (55%)	Gaps:	15/272 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1054 ERWELSNDDVVLLERIGRGNFGDVYKAKLK---STKLDVAVKTCRMTLPDEQKRKFLQEGRILKQ 1115
            ::||:..|.||:..|:|.|.||.||..:.:   .....|||||.::....|.|..||.|...:|:
Mosquito     5 DKWEIPKDRVVINRRLGEGAFGTVYGGEAQIGDEGWTAVAVKTLKVGSTTEDKVDFLSEAEAMKR 69

  Fly  1116 YDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYL----------RKNSNGLTTRQQMGMCRDAA 1170
            :||.|||:|:|:|:|.:|:..|||.:|.|.|.|||          :...:.::.::...|..|.:
Mosquito    70 FDHNNIVRLLGVCLQSEPVYTVMEFMLYGDLKTYLLARRHLVNSKQSEDSDISNKRLTMMALDVS 134

  Fly  1171 AGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSRE--EEEYIVSDGMKQIPVKWTAPEALN 1233
            ..:.||..:..:|||:|.|||:|:.:..||:.||||:|.  |.:|...:....:||:|.|||:|.
Mosquito   135 RALSYLAEQKYVHRDVACRNCMVNAQRVVKLGDFGMARPTFENDYYRFNRRGMLPVRWMAPESLG 199

  Fly  1234 FGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWA 1298
            .|.:|...||||||:|::||.:.|..|:.|:||::..|.:..|..:..|.....::..||..||.
Mosquito   200 LGIFTPASDVWSYGVLLYEIITFGSFPFQGLTNNQVLEHLKNGNTITIPAGVKPQLEGLMKACWN 264

  Fly  1299 ADAESRPHFDEI 1310
            .|.:.||...|:
Mosquito   265 QDYKKRPSASEV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	94/263 (36%)
		PTKc_Fes_like	1067..1315	CDD:270637	92/259 (36%)
AgaP_AGAP009157	XP_001238225.2	STYKc	14..280	CDD:214568	94/263 (36%)
AgaP_AGAP009157	XP_001238225.2	PTKc	18..280	CDD:270623	92/259 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910