DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and slpr

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	101/374 - (27%)
Similarity:	158/374 - (42%)	Gaps:	88/374 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   985 TIRNEESQIVLSV---------CWNGH---------KHFIVQTTGEGNFRFEGPPFASIQELIMH 1031
            |:|..|..:|||.         .|.|.         |.|:..         |.|
  Fly    63 TLRRGEIVVVLSTDSEVSGDVGWWTGKIGDKVGVFPKDFVTD---------EDP----------- 107

  Fly  1032 QYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRM 1096
               .:|.|:...|.|       :..|:..:::.:.|.||.|.|..|::......  :||:|....
  Fly   108 ---LQLNVSSAIGDI-------QPHEIEYNELDIKEVIGSGGFCKVHRGYYDGE--EVAIKIAHQ 160

  Fly  1097 TLPDEQKR---KFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLT 1158
            |..|:.:|   ..|||.::.....|.||..|.|:|:..: :.:|||...||||...|   :..:.
  Fly   161 TGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTK-LCLVMEYARGGSLNRIL---AGKIP 221

  Fly  1159 TRQQMGMCRDAAAGMRYLESK---NCIHRDLAARNCL----VDLEH----SVKISDFGMSRE--E 1210
            ....:......|.||.||.::   :.|||||.:.|.|    ::..|    ::||:|||::||  .
  Fly   222 PDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYN 286

  Fly  1211 EEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDT 1275
            .:.:.:.|    ...|..||.::...|:...||||||:|:||:.: |:|||.|.      :.:..
  Fly   287 TQRMSAAG----TYAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKGF------DPLSV 340

  Fly  1276 GY-------RMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
            .|       .:|.||:.||....||..||..|...||.|.||...::::
  Fly   341 AYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	13/71 (18%)
		TyrKc	1063..1311	CDD:197581	83/270 (31%)
		PTKc_Fes_like	1067..1315	CDD:270637	84/270 (31%)
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	10/40 (25%)
		TyrKc	129..386	CDD:197581	84/273 (31%)
		STKc_MLK	134..389	CDD:270963	83/271 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810