DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and cdi

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_524401.2	Gene:	cdi / 42289	FlyBaseID:	FBgn0004876	Length:	1213	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	91/351 - (25%)
Similarity:	148/351 - (42%)	Gaps:	58/351 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1007 VQTTGEGNFRFEGPPFASIQELIMHQ-YHS---------ELPV--TVKSGAILRRPVCRE-RWEL 1058
            |.|:..|:...|.|        :.|| .|:         ..||  |:.|..::....||. |..:
  Fly    46 VTTSTNGDATAEAP--------VKHQPLHNGGWIGNGLPPAPVTRTISSDRLVTGSSCRALRTAV 102

  Fly  1059 SN----DDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHP 1119
            |.    ||.| .|:||.|.|.:|||...::|.   .|...:|......:...|:|.::|.:..|.
  Fly   103 SALYSVDDFV-KEKIGSGFFSEVYKVTHRTTG---QVMVLKMNQLRANRPNMLREVQLLNKLSHA 163

  Fly  1120 NIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHR 1184
            ||:..:|:|||:..:..:.|.:.||||...|......|:..|::.:....|.||.|:......||
  Fly   164 NILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHR 228

  Fly  1185 DLAARNCLV----DLEHSVKISDFGMSREEEEYIVSDGMKQIPVK-------------WTAPEAL 1232
            ||.::|.|:    :.::...:.|||::            .:||||             |.:||.|
  Fly   229 DLTSKNVLIRNLANDQYEAVVGDFGLA------------AKIPVKSRKSRLETVGSPYWVSPECL 281

  Fly  1233 NFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCW 1297
            ....|....||:|:||:..||.::.:.....|..:.:.......:....|..||....||...|.
  Fly   282 KGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPMDTPPVFLRLAFYCC 346

  Fly  1298 AADAESRPHFDEIYNVVDALILRLDN 1323
            ..||:|||.|.:....:..|:.:.::
  Fly   347 LYDAKSRPTFHDATKKLTLLLEKYEH 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	8/41 (20%)
		TyrKc	1063..1311	CDD:197581	72/264 (27%)
		PTKc_Fes_like	1067..1315	CDD:270637	71/264 (27%)
cdi	NP_524401.2	TyrKc	113..363	CDD:197581	71/264 (27%)
cdi	NP_524401.2	PKc_like	116..370	CDD:304357	71/268 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910