DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and Tak1

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_524080.1	Gene:	Tak1 / 39659	FlyBaseID:	FBgn0026323	Length:	678	Species:	Drosophila melanogaster

Alignment Length:	263	Identity:	81/263 - (30%)
Similarity:	131/263 - (49%)	Gaps:	15/263 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1062 DVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIG 1126
            ::.|.|::|.|::|.|.||..:. || ||||.   .....:::...:|.:.|.:..||||:.|.|
  Fly    18 EITLREKVGHGSYGVVCKAVWRD-KL-VAVKE---FFASAEQKDIEKEVKQLSRVKHPNIIALHG 77

  Fly  1127 ICVQKQPIMIVMELVLGGSLLTYLR-KNSNGLTTRQQMGMCRDAAAGMRYLES---KNCIHRDLA 1187
            |...:|...::||...||||..:|. |.....:....|...|..|.|:.||.:   |..||||:.
  Fly    78 ISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVK 142

  Fly  1188 ARNCLV-DLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMW 1251
            ..|.|: :...::||.|||...::...:.::   :....|.|||.....|||..||::|:.|::|
  Fly   143 PLNLLLTNKGRNLKICDFGTVADKSTMMTNN---RGSAAWMAPEVFEGSKYTEKCDIFSWAIVLW 204

  Fly  1252 EIFSKGDTPYSGMTNSRARE-RIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVD 1315
            |:.|: ..|:.|:.|:...: :|..|.|.|...:.|:.:..||..||....|.||....|..|:.
  Fly   205 EVLSR-KQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMH 268

  Fly  1316 ALI 1318
            .::
  Fly   269 EIV 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	79/253 (31%)
		PTKc_Fes_like	1067..1315	CDD:270637	80/253 (32%)
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	79/253 (31%)
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	79/256 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910