Protein Alignment FER and btl

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001014583.1
• Gene: btl / 39564
• FlyBaseID: FBgn0285896
• Length: 1052
• Species: Drosophila melanogaster
• Alignment Length: 1151
• Identity: 247/1151 - (21%)
• Similarity: 401/1151 - (34%)
• Gaps: 377/1151 - (32%)

  Fly   385 LVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLT 449
            ::..|..|..::||:.....|..|:|:|        |:.:||.         :::::   ...|.
  Fly    10 MIIAIVSAAADLGCDYGHHRCYIDVTVE--------NSPRQRH---------LLSDM---DITLQ 54

  Fly   450 LLRGRGRHFKRKSTPQPATPMTRSR-----QGRFNKLQPRSQSLGSLSVIRDGNGPSPARYEPIT 509
            .:|...:.|........||.:...|     .|.:..|..:::......|:        ...||:
  Fly    55 CVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWYNISLVV--------GHKEPV- 110

  Fly   510 NHRLRQAASVHYLGEEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLT-QLTAAVLT 573
                         |.:|| |.....|...|..:......|.|... :.|..|.|.| |.||..|.
  Fly   111 -------------GNDIA-SFVKLEDAPALPESDLFFQPLNESRS-LKLLQPLPKTVQRTAGGLF 160

  Fly   574 NTNNNHIYADLELDKKKDTSP-SPECKGEQIQPKKEQIRIEINQTAPQNSIDAHLDRIDELNRVL 637
            ..|               .|| .|:.||           :.|:.......|.....||
  Fly   161 QLN---------------CSPMDPDAKG-----------VNISWLHNDTQILGGRGRI------- 192

  Fly   638 DDRLKR------TLQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDT----- 691
              :|||      .|||.|       |...|.:   |..:.|.|  ||:.:..|..|.|.|
  Fly   193 --KLKRWSLTVGQLQPED-------AGSYHCE---LCVEQDCQ--RSNPTQLEVISRKHTVPMLK 243

  Fly   692 -SHSKKRSLSFSQK-------------------------SISNIFSNLKEFSKSP------LVRM 724
             .:.:..|::....                         :|.::...|:|.|:.|      :.||
  Fly   244 PGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRM 308

  Fly   725 GKNHILN----------------EEQDAKRTQPSQHHHSSGSD-------------CPTNSSSSS 760
            .:..:|.                |.|..:....|.....|.||             .|..::|:.
  Fly   309 DEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTTVRTTTTTTVASPIPTASTG 373

  Fly   761 SNNNNNNKNTSSNSN----------------HSASQSTIITSTITTTITTTTTTTPSKENSRLKF 809
            .:|:::.:|.::.::                ||.|.:|:   .:...:......|.:|:...|..
  Fly   374 EDNDDDVENPAAEASGGVGPPVFRKELKRLQHSLSGNTV---NLACPVYGKANITWTKDKKPLNR 435

  Fly   810 KVPKIQKKSKAIR----NTFRSKLLNFQLKRSKPCKQCTKRRRIHPSKSVFDFAKEFEVEQPAGS 870
            ::....:|:..:|    .:..|.|.|        ||.|.....|.     |||:  .::.....|
  Fly   436 ELGVYVQKNWTLRFVEATSEDSGLYN--------CKVCNAWGCIQ-----FDFS--VQINDRTRS 485

  Fly   871 AADEQFCNCPPAGQKPVKPSVQISG--------HKD-HPFES------SSGELD-------ENSD 913
            |         |....|...:|:::|        :.| ||..|      .:..||       :|.:
  Fly   486 A---------PIIVVPQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLKSVEIQNLN 541

  Fly   914 RDIDNDEEEEDSASDDVLSMKDHCY-------CVPSLA-----ASISLSTNRPLYEEEWFHGVLP 966
            ..:.||..        ||::::..:       |:.|..     :|:.|....|          ||
  Fly   542 FTVTNDSV--------VLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSP----------LP 588

  Fly   967 REEVVRLLNNDG---------------------DFLVR------------ETIRNEESQIVL--- 995
            ..|:..||:...                     .|::|            ||:.....::::
  Fly   589 PLEIYALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRP 653

  Fly   996 -----SVCWNG----------HKHFIVQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGA 1045
                 |.|.:|          .:...|.|||.|.    ..|.....|.       |.|:.
  Fly   654 GGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGG----TDPAQGFNEY-------EFPLD----- 702

  Fly  1046 ILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKL----KSTKLD---VAVKTCRMTLPDEQK 1103
                    ..||:....:.|...:|.|.||.|..|:.    :|.:|.   ||||..:....|...
  Fly   703 --------SNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDM 759

  Fly  1104 RKFLQEGRILKQY-DHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNG----------- 1156
            ...::|..::|.. .|.||:.|:|.|.|..|:.:::|....|:|..:|::|..|
  Fly   760 ASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGY 824

  Fly  1157 -----LTTRQQMG------MCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSR-- 1208
                 |.:.|.:|      .....|.||.||.|:.||||||||||.||...:.:||:|||::|
  Fly   825 LDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDI 889

  Fly  1209 EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNS-RARER 1272
            ::.||...:...::|:||.|||:|...||.|..||||||:|:|||.:.||.||..:.:: .....
  Fly   890 QDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSY 954

  Fly  1273 IDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALI 1318
            :.||.||..|......:|.:|.|||..::.:||.|.|:....|.::
  Fly   955 LITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGIL 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	21/136 (15%)
		TyrKc	1063..1311	CDD:197581	97/280 (35%)
		PTKc_Fes_like	1067..1315	CDD:270637	96/280 (34%)
btl	NP_001014583.1	IG_like	149..232	CDD:214653	30/129 (23%)
		IGc2	157..215	CDD:197706	20/99 (20%)
		IG	247..336	CDD:214652	11/88 (13%)
		Ig	258..340	CDD:143165	10/81 (12%)
		I-set	394..479	CDD:254352	19/102 (19%)
		IGc2	408..469	CDD:197706	13/71 (18%)
		IG_like	492..583	CDD:214653	18/98 (18%)
		Ig	507..583	CDD:299845	15/83 (18%)
		PKc_like	700..1000	CDD:304357	101/312 (32%)
		TyrKc	712..996	CDD:197581	97/283 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810