DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and drk

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	48/200 - (24%)
Similarity:	81/200 - (40%)	Gaps:	49/200 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   899 HPFESSSGELDENSDR--------DIDND--------EEEEDSASDDVLSMKDHCYCVPSLAASI 947
            |.|.:::.  ||.|.|        ::::|        :.:|.....:.:.||:|
  Fly     7 HDFSATAD--DELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNH----------- 58

  Fly   948 SLSTNRPLYEEEWFHGVLPREEVVRLLNN--DGDFLVRETIRNEESQIVLSV-CWNGHKHFIVQT 1009
                       :|::|.:.|.:..:||:|  :|.||:|.: .:......||| |.:|.:||.|..
  Fly    59 -----------DWYYGRITRADAEKLLSNKHEGAFLIRIS-ESSPGDFSLSVKCPDGVQHFKVLR 111

  Fly  1010 TGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNF 1074
            ..:..|......|.|:.||:  :||....|:......||..:..|....:..|.|..|. |..:|
  Fly   112 DAQSKFFLWVVKFNSLNELV--EYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQES-GELDF 173

  Fly  1075 --GDV 1077
              |||
  Fly   174 RRGDV 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	25/88 (28%)
		TyrKc	1063..1311	CDD:197581	6/16 (38%)
		PTKc_Fes_like	1067..1315	CDD:270637	5/12 (42%)
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	8/47 (17%)
		SH2_Grb2_like	56..149	CDD:199828	29/117 (25%)
		SH3_GRB2_like_C	156..208	CDD:212739	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000