DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and dnt

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001260567.1	Gene:	dnt / 35207	FlyBaseID:	FBgn0024245	Length:	584	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	84/287 - (29%)
Similarity:	137/287 - (47%)	Gaps:	26/287 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1030 MHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTC 1094
            :|:..|||  ||:.        ||.|         |...:..|.||.||:.....|: ||.|||.
  Fly   303 LHRRISEL--TVER--------CRVR---------LSSLLQEGTFGRVYRGTYNDTQ-DVLVKTV 347

  Fly  1095 RMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGG--SLLTYLRKN--SN 1155
            .......|....||||.:|....||.|:.::|:.::......|:...|..  :|..:|...  :.
  Fly   348 AQHASQMQVLLLLQEGMLLYGASHPGILSVLGVSIEDHTTPFVLYPALNNTRNLKQFLLDPACAR 412

  Fly  1156 GLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSRE--EEEYIVSDG 1218
            .:||.|.:.|....:..:.:|.|...:|:|:|.|||::|.:..||:||..:||:  ..:|.....
  Fly   413 TVTTIQIVMMASQLSMALDHLHSHGVVHKDIATRNCVIDDQLRVKLSDSSLSRDLFPSDYNCLGD 477

  Fly  1219 MKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPK 1283
            .:..||||.:.|||...:::...|.|::|:||||:.:....||:.:........:..|||:..|.
  Fly   478 SENRPVKWMSLEALQHKQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGYRLAQPF 542

  Fly  1284 STPEEMYRLMLQCWAADAESRPHFDEI 1310
            :.|:|::.:|..|||.....||.|.::
  Fly   543 NCPDELFTIMAYCWALLPAERPTFAQL 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	4/8 (50%)
		TyrKc	1063..1311	CDD:197581	75/254 (30%)
		PTKc_Fes_like	1067..1315	CDD:270637	74/250 (30%)
dnt	NP_001260567.1	WIF	46..182	CDD:128745
		PKc_like	310..580	CDD:304357	81/280 (29%)
		Pkinase_Tyr	317..573	CDD:285015	76/263 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910