DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and CG10702

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	60/329 - (18%)
Similarity:	108/329 - (32%)	Gaps:	122/329 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVAQQGLKIDRADEMQGSLISK 71
            |::|  |.:.|:..:.||..:.|..|.::.               .:.|:.:.|    ...|.::
  Fly   388 LENR--HYSFILYDNKELSELWTPSRQLEF---------------MEGGMFMHR----NNKLCNR 431

  Fly    72 SWRSYMDELDHQAKQFKFNAEQLEVVC---------DKLTH--------LSQDKRKAR------- 112
            ..|.:.:.:.|............||.|         .|.||        .||..:|..
  Fly   432 RMREFQNAVTHDRALDSLQTNDQEVQCSPLKLQLYVQKRTHRSVKLSWLKSQTSQKIELIHRPLL 496

  Fly   113 --KAYQEE---HAKIAARLNH-----LTDEVVRKKSEYQKHL-------------------EGYK 148
              |.|.||   .|.|..|:|.     ..|:::...:.|...|                   |.::
  Fly   497 PGKLYHEESELDAPICTRINWKRRLLFPDDLIENGTHYLFDLDDLQPDTRYVVLLRTFGNDEAHE 561

  Fly   149 ALRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKL--HLT-------HNEYVLSITEAIEVEKDF 204
            |...|.|..|::.      :||..:....:..:|.  .||       |..::|::.| :..::|:
  Fly   562 AYEARSELTYVQT------ELDIPKPPLLELVKKTDSSLTVQMASHDHVSFLLTVFE-LSDDQDY 619

  Fly   205 ---RNVLLPGLLEHQQSVQESFILLWRNI---------------LQEAAQYGD--LTADKYKEIQ 249
               ||..      ||.|      .:|:::               .|:|.|:.|  ..||..::.:
  Fly   620 IEQRNYC------HQPS------YVWQDMDGPRWMAYEDYDDCCAQKAEQFEDSRFIADMREQYR 672

  Fly   250 KRID 253
            ..:|
  Fly   673 CTLD 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341	57/317 (18%)
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142
		FU	210..258	CDD:238021
		Recep_L_domain	328..441	CDD:279382	12/73 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468371
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930