Protein Alignment FER and AgaP_AGAP005976

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_556653.3
• Gene: AgaP_AGAP005976 / 3290080
• VectorBaseID: AGAP005976
• Length: 604
• Species: Anopheles gambiae
• Alignment Length: 640
• Identity: 123/640 - (19%)
• Similarity: 220/640 - (34%)
• Gaps: 191/640 - (29%)

  Fly     3 FSSALQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVAQQGLKIDRADEMQGS 67
            |...::.|:|.|.     :..|:|...:|.....|:|.|:|...|                   |
Mosquito    33 FGGFIRDRSAIEV-----EYALKLRRLVKNYQPKKSKEDEENEFS-------------------S 73

  Fly    68 LISKSWRSYMDELDHQAKQFKFNAEQLE-VVCDKLTHLSQDKRKARKAYQEEHAKIAARLNHLTD 131
            ||  ::::.:.|:...|.|.:..||.|: .|...:..|:::.|:.||....:.|.:...|:....
Mosquito    74 LI--AFKNVLKEVADLAGQREVVAENLQNQVLQGILLLAKNLREERKKALNQGASLTQSLHTQIG 136

  Fly   132 EVVRKKSEYQKHL-EGYKALRTRFEENYIKAP-----SRS------------GRKLDDVRDKYQK 178
            .:.|.|..|:|.. |..||:     |:|.||.     ||:            ..:.:|.:.:|
Mosquito   137 TLDRAKRSYEKAFREAEKAI-----ESYHKADADFHLSRADVEKQRVNMNIRNSQSEDAKSEY-- 194

  Fly   179 ACRKLHLTHNEYVLSITEAIEVEKDFRNVLLPGLLEHQQSVQESFILLWRNILQEAA----QYGD 239
             ..:|.:|:.:           ::....:.||.:....|.:.|......:..::.:|    :...
Mosquito   195 -ANQLQITNKQ-----------QQQHYQIALPEVFNRLQELDEKRTRGMKEFIKRSADVEYEVSP 247

  Fly   240 LTADKYKEIQKRIDTVIGSINPTEEYGEFTEKYKTSPTTPLLFQFDE------------------ 286
            :.|...:.|.|..|    |||..::.....|||::....|....|::
Mosquito   248 IIAHCLEGIVKAAD----SINEKDDSMIVIEKYQSGFQPPGDIPFEDLSKPDPDAANNSQTHNSS 308

  Fly   287 TLIQDIPGKLQSS-------------TLTVDNLTVDWLR---------NRLQELEGAVRDCQEKQ 329
            |.:..:.||..:.             |...:||:.|.|:         .|.::|...|::.|:|
Mosquito   309 TGLNHMTGKGTTKDKLKKRVGIFGIFTGNKNNLSTDGLKEDFSDLPPTQRRKKLTAKVQELQQK- 372

  Fly   330 MKMIEHVNGGSPVANGSIISNGSNTSNGI-QSN---------KDSLCRQSKDLNALRCQEKQKQK 384
                        ||.....|:|.....|: ::|         ::.|......|:.||.:..:.||
Mosquito   373 ------------VAQEQAASDGLMKMKGVYEANSMLGDPRTVEEQLNESVNRLDRLRHELLRYQK 425

  Fly   385 LVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGY------NNEQQRSNSTSSPG------LGI 437
            |::.   |.|:...:..|.        ....|:||.      |......||....|      .|.
Mosquito   426 LLEQ---ANNQSFIQHSPQ--------SNRVIQNGQRSSRHSNGSSNHENSHEDNGEDHPDDAGS 479

  Fly   438 MNELMRRGGVLTLLRGRGRHFKRKSTPQPA-----TPMTRSRQGRFNKLQPRSQS-------LGS 490
            ::.......|.....|...:....::|:..     |.:..|.||..|: ||.::.       ||:
Mosquito   480 LSRSASESSVQQAQNGLNINNNGSASPESGLGTSHTSLPGSGQGSTNE-QPMNEEFYEADTPLGT 543

  Fly   491 LSVIRDGNGPSPARYE---PITNHRLRQAASVHYLGEEIATSSTNPPD-LTRLRR 541
            ...:.    |..|..|   |::.            |||:.....:..| .||:||
Mosquito   544 CRALY----PFDATSEGSIPMSE------------GEELQVIEVDQGDGWTRVRR 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341	49/258 (19%)
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
AgaP_AGAP005976	XP_556653.3	F-BAR_CIP4-like	14..261	CDD:153337	53/272 (19%)
		HR1_CIP4-like	355..431	CDD:212009	18/91 (20%)
		SH3_CIP4-like	543..600	CDD:212844	12/56 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910