DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and Wsck

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	68/280 - (24%)
Similarity:	121/280 - (43%)	Gaps:	39/280 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1053 RERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKL--DVAVKT-CRMTLPDEQKRKFLQEGR--- 1111
            |....|:.:||     ||.|.||::...|:.:...  |..:.. |...|....:.:.|:|.|
  Fly   488 RNALRLNVNDV-----IGDGRFGEIITGKVSTNDFARDCTLHVLCLDDLNGTTQAQLLRELRQLS 547

  Fly  1112 ILKQYDHPNIVKLIGICVQKQPIMIVME---LVLGGSLL-TYLRKNSNGLTTRQQMGMCR---DA 1169
            .||:.:|  ::...|:........::.|   :.|...|: :.|...|..||:..:..:.:   :.
  Fly   548 QLKRQEH--LLDFYGVSASPDWFYLIFEQQRMSLKRKLVESRLMAPSPRLTSLSEQLVLQWIYEL 610

  Fly  1170 AAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFG------MSREEEEYIVSDGMKQIPVKWTA 1228
            |:.|.||.|...:||.|.:.:..|..:..:|:|.||      ::|::.::          .:|.|
  Fly   611 ASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFGPLPYMNIARQQPDH----------NRWLA 665

  Fly  1229 PEALNFGKYTSL-CDVWSYGILMWEIFSKGDTPYSG--MTNSRARERIDTGYRMPTPKSTPEEMY 1290
            ||.|....:.|. .||||...:.||..:.|.|||:.  .:|.:..|.|....|...|.....::|
  Fly   666 PEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYANAVASNQQLLEAIRAAVRPAQPAYVYGDLY 730

  Fly  1291 RLMLQCWAADAESRPHFDEI 1310
            :|:|.||..:...|...:::
  Fly   731 QLLLNCWQLEPSERSSCEDV 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	65/270 (24%)
		PTKc_Fes_like	1067..1315	CDD:270637	64/266 (24%)
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	67/269 (25%)
		PTKc	497..750	CDD:270623	66/269 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24418
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100