Protein Alignment FER and Map3k11

DIOPT Version :10

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001013168.1
• Gene: Map3k11 / 309168
• RGDID: 1359261
• Length: 850
• Species: Rattus norvegicus
• Alignment Length: 297
• Identity: 95/297 - (31%)
• Similarity: 139/297 - (46%)
• Gaps: 59/297 - (19%)

  Fly  1059 SNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQ----KRKFLQEGRILKQYDHP 1119
            |..::.|.|.||.|.||.||:...:...  ||||..|.. |||.    .....||.|:.....||
  Rat   114 SFQELRLEEVIGIGGFGKVYRGSWRGEL--VAVKAARQD-PDEDISVTAESVRQEARLFAMLAHP 175

  Fly  1120 NIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQ-----QMGMCRDAAAGMRYLESK 1179
            ||:.|..:|:::..:.:|||...||.|       |..|..|:     .:......|.||.||
  Rat   176 NIIALKAVCLEEPNLCLVMEYAAGGPL-------SRALAGRRVPPHVLVNWAVQIARGMHYL--- 230

  Fly  1180 NC------IHRDLAARNCLV-------DLEH-SVKISDFGMSRE--EEEYIVSDGMKQIPVKWTA 1228
            :|      |||||.:.|.|:       |:|| ::||:|||::||  :...:.:.|    ...|.|
  Rat   231 HCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAG----TYAWMA 291

  Fly  1229 PEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGY-------RMPTPKSTP 1286
            ||.:....::...||||:|:|:||:.: |:.||.|:      :.:...|       .:|.|.:.|
  Rat   292 PEVIKASTFSKGSDVWSFGVLLWELLT-GEVPYRGI------DCLAVAYGVAVNKLTLPIPSTCP 349

  Fly  1287 EEMYRLMLQCWAADAESRPHFDEIYNVVDAL---ILR 1320
            |...:||..|||.|...||.|..|...::||   :||
  Rat   350 EPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		PTKc_Fes_like	1067..1315	CDD:270637	89/279 (32%)
Map3k11	NP_001013168.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..37
		SH3_MLK1-3	46..103	CDD:212992
		STKc_MLK3	114..380	CDD:271049	91/289 (31%)
		Leucine-zipper 1	404..425
		Leucine-zipper 2	439..460
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	536..850