Protein Alignment FER and Zap70

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001276695.1
• Gene: Zap70 / 22637
• MGIID: 99613
• Length: 642
• Species: Mus musculus
• Alignment Length: 535
• Identity: 151/535 - (28%)
• Similarity: 230/535 - (42%)
• Gaps: 122/535 - (22%)

  Fly   861 EFEVEQPAGSAAD-EQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDND--EEE 922
            :|..:.|.|...: .:.||.|| |.:| :|.|         |:.    |.:...||....  :.|
Mouse   109 QFYSQDPDGLPCNLRKPCNRPP-GLEP-QPGV---------FDC----LRDAMVRDYVRQTWKLE 158

  Fly   923 EDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLL----NNDGDFLVR 983
            .|:....::|.      .|.:...|:.:.:..:   .|:|..|.|||..|.|    ..||.||:|
Mouse   159 GDALEQAIISQ------APQVEKLIATTAHERM---PWYHSSLTREEAERKLYSGQQTDGKFLLR 214

  Fly   984 ETIRNEESQIVLSVCWNGH-KHFIVQTTGEGNFRF-EGPPFASIQELIMHQYHSELPVTVKSGAI 1046
            .  |.|:....||:.:... .|:::.....|.:.. ||..|.::.:|:.:       :.:|:..:
Mouse   215 P--RKEQGTYALSLVYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEY-------LKLKADGL 270

  Fly  1047 LRR--PVC------------------------RERWELSNDD----------------------- 1062
            :.|  .||                        :.|.:..|.|
Mouse   271 IYRLKEVCPNSSASAAVAAPTLPAHPSTFTQPQRRVDTLNSDGYTPEPARLASSTDKPRPMPMDT 335

  Fly  1063 ----------------VVLLER---------IGRGNFGDVYKA--KLKSTKLDVAVKTCRMTLPD 1100
                            .:.|:|         :|.||||.|.:.  :::..::|||:|..:.....
Mouse   336 SVYESPYSDPEELKDKKLFLKRENLLVADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEK 400

  Fly  1101 EQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGM 1165
            ..|.:.::|.:|:.|.|:|.||:|||:| |.:.:|:|||:..||.|..:|......:.......:
Mouse   401 ADKDEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEMAGGGPLHKFLLGKKEEIPVSNVAEL 464

  Fly  1166 CRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSR---EEEEYIVSDGMKQIPVKWT 1227
            ....|.||:|||.||.:||||||||.|:...|..||||||:|:   .::.|..:....:.|:||.
Mouse   465 LHQVAMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWY 529

  Fly  1228 APEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRL 1292
            |||.:||.|::|..||||||:.|||.||.|..||..|......:.|..|.||..|...|.|||.|
Mouse   530 APECINFRKFSSRSDVWSYGVTMWEAFSYGQKPYKKMKGPEVLDFIKQGKRMECPPECPPEMYAL 594

  Fly  1293 MLQCWAADAESRPHF 1307
            |..||....|.||.|
Mouse   595 MSDCWIYKWEDRPDF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	23/91 (25%)
		TyrKc	1063..1311	CDD:197581	101/259 (39%)
		PTKc_Fes_like	1067..1315	CDD:270637	100/255 (39%)
Zap70	NP_001276695.1	SH2_N-SH2_Zap70_Syk_like	32..135	CDD:198191	9/27 (33%)
		SH2	176..280	CDD:301589	28/115 (24%)
		PTKc_Zap-70	356..624	CDD:270686	100/255 (39%)
		Pkinase_Tyr	366..616	CDD:285015	99/245 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910