DRSC/TRiP Functional Genomics Resources

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Protein Alignment FER and Tesk1

DIOPT Version :9

Sequence 1:NP_524288.3 Gene:FER / 41118 FlyBaseID:FBgn0000723 Length:1325 Species:Drosophila melanogaster
Sequence 2:NP_035701.3 Gene:Tesk1 / 21754 MGIID:1201675 Length:627 Species:Mus musculus


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FERNP_524288.3 F-BAR_Fes_Fer 7..243 CDD:153341
SH2_Fps_family 953..1039 CDD:198224
TyrKc 1063..1311 CDD:197581
PTKc_Fes_like 1067..1315 CDD:270637
Tesk1NP_035701.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36
TyrKc 56..306 CDD:197581
PKc_TESK 58..312 CDD:271057
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 316..373
Required for interaction with YWHAB. /evidence=ECO:0000250|UniProtKB:Q63572 421..525
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 436..485
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 500..519
Required for interaction with SPRED1 and SPRY2. Required for TESK1-mediated dephosphorylation of SPRY2 and SPRY2 inhibition of ERK phosphorylation. /evidence=ECO:0000250|UniProtKB:Q63572 528..627
Required for interaction with PARVA. /evidence=ECO:0000250|UniProtKB:Q63572 528..625
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 532..565
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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