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Protein Alignment FER and ERBB2

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_024306409.1	Gene:	ERBB2 / 2064	HGNCID:	3430	Length:	1301	Species:	Homo sapiens

Alignment Length:	281	Identity:	94/281 - (33%)
Similarity:	154/281 - (54%)	Gaps:	15/281 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1038 PVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKA----KLKSTKLDVAVKTCRMTL 1098
            |:| .|||:..:...|   .|...::..::.:|.|.||.|||.    ..::.|:.||:|..|...
Human   745 PLT-PSGAMPNQAQMR---ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENT 805

  Fly  1099 PDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQM 1163
            ..:..::.|.|..::.....|.:.:|:|||: ...:.:|.:|:..|.||.::|:|...|.::..:
Human   806 SPKANKEILDEAYVMAGVGSPYVSRLLGICL-TSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLL 869

  Fly  1164 GMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSR----EEEEYIVSDGMKQIPV 1224
            ..|...|.||.|||....:||||||||.||...:.|||:|||::|    :|.||....|  ::|:
Human   870 NWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGG--KVPI 932

  Fly  1225 KWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEM 1289
            ||.|.|::...::|...||||||:.:||:.:.|..||.|:......:.::.|.|:|.|.....::
Human   933 KWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDV 997

  Fly  1290 YRLMLQCWAADAESRPHFDEI 1310
            |.:|::||..|:|.||.|.|:
Human   998 YMIMVKCWMIDSECRPRFREL 1018

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.