| Sequence 1: | NP_524288.3 | Gene: | FER / 41118 | FlyBaseID: | FBgn0000723 | Length: | 1325 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001296122.1 | Gene: | EPHB2 / 2048 | HGNCID: | 3393 | Length: | 1055 | Species: | Homo sapiens |
| Alignment Length: | 692 | Identity: | 187/692 - (27%) |
|---|---|---|---|
| Similarity: | 275/692 - (39%) | Gaps: | 210/692 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 752 CPTNSSSSSSNNNN---NNKNTSSNSNHSASQSTIITSTITTTITTTTTT------TPSKENSRL 807
Fly 808 KFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCKQCTKRR----------------------RIH 850
Fly 851 PSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKP---SVQISGHKDHPFESSSGELDENS 912
Fly 913 DRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRP--------LYEEEWFHGVLPREE 969
Fly 970 VVRLLNNDGD-------------FLVR-ETIRNEESQIVLSVCWNGHKHFIVQTTGEGNFRFEGP 1020
Fly 1021 PFASIQELIMHQYHSELPVTVKSGA---------ILRRPVCRER--------------------- 1055
Fly 1056 ------------WELSNDDV-----------VLLER-IGRGNFGDVYKAKLK---STKLDVAVKT 1093
Fly 1094 CRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLT 1158
Fly 1159 TRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEE------YIVSD 1217
Fly 1218 GMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTP 1282
Fly 1283 KSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDNS 1324 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FER | NP_524288.3 | F-BAR_Fes_Fer | 7..243 | CDD:153341 | |
| SH2_Fps_family | 953..1039 | CDD:198224 | 18/107 (17%) | ||
| TyrKc | 1063..1311 | CDD:197581 | 114/268 (43%) | ||
| PTKc_Fes_like | 1067..1315 | CDD:270637 | 114/257 (44%) | ||
| EPHB2 | NP_001296122.1 | EphR_LBD_B2 | 19..196 | CDD:198445 | |
| fn3 | 326..421 | CDD:278470 | 19/129 (15%) | ||
| fn3 | 437..520 | CDD:278470 | 15/117 (13%) | ||
| EphA2_TM | 548..616 | CDD:291255 | 7/67 (10%) | ||
| PTKc_EphR_B | 616..884 | CDD:173638 | 116/268 (43%) | ||
| Pkinase_Tyr | 621..880 | CDD:285015 | 115/259 (44%) | ||
| SAM_EPH-B2 | 910..980 | CDD:188951 | |||
| SAM | 910..977 | CDD:197735 | |||
| PDZ-binding (in isoform 2). /evidence=ECO:0000255 | 984..986 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 990..1055 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||