Protein Alignment FER and Mst1r

DIOPT Version :10

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_006511717.1
• Gene: Mst1r / 19882
• MGIID: 99614
• Length: 1406
• Species: Mus musculus
• Alignment Length: 289
• Identity: 91/289 - (31%)
• Similarity: 151/289 - (52%)
• Gaps: 39/289 - (13%)

  Fly  1069 IGRGNFGDVYKAKL---KSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQ 1130
            ||:|:||.||..:.   ...:...|:|:.......::...||:||.:::...||||:.||||.:.
Mouse  1066 IGKGHFGVVYHGEYTDGAQNQTHCAIKSLSRITEVQEVEAFLREGLLMRGLHHPNILALIGIMLP 1130

  Fly  1131 KQPI-MIVMELVLGGSLLTYLR--------------KNSNGLTTRQQMGMC------RD------ 1168
            .:.: .:::..:..|.||.::|              ..|.....|..:.:|      :|
Mouse  1131 PEGLPRVLLPYMRHGDLLHFIRSPQRVSDHCPGWEVSASTHPCLRSPVTLCPQNPTVKDLVSFGL 1195

  Fly  1169 -AAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSR---EEEEYIVSDGM-KQIPVKWTA 1228
             .|.||.||..:..:|||||||||::|...:||::|||::|   ::|.|.|.... .::||||.|
Mouse  1196 QVACGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARGVLDKEYYSVRQHRHARLPVKWMA 1260

  Fly  1229 PEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLM 1293
            .|:|...::|:..||||:|:|:||:.::|..||..:........:..|.|:|.|:..|:.:|.:|
Mouse  1261 LESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQGRRLPQPEYCPDSLYHVM 1325

  Fly  1294 LQCWAADAESRPHFD----EIYNVVDALI 1318
            |:||.||..:||.|.    |:..||.:|:
Mouse  1326 LRCWEADPAARPTFRALVLEVKQVVASLL 1354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		PTKc_Fes_like	1067..1315	CDD:270637	89/284 (31%)
Mst1r	XP_006511717.1	Sema_RON	29..525	CDD:200540
		PSI	528..570	CDD:396154
		IPT	571..685	CDD:472823
		IPT_plexin_repeat2	686..770	CDD:238584
		IPT	771..864	CDD:214657
		Protein Kinases, catalytic domain	1064..1352	CDD:473864	90/285 (32%)