DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FER and Mst1r

DIOPT Version :9

Sequence 1:NP_524288.3 Gene:FER / 41118 FlyBaseID:FBgn0000723 Length:1325 Species:Drosophila melanogaster
Sequence 2:XP_006511717.1 Gene:Mst1r / 19882 MGIID:99614 Length:1406 Species:Mus musculus


Alignment Length:289 Identity:91/289 - (31%)
Similarity:151/289 - (52%) Gaps:39/289 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly  1069 IGRGNFGDVYKAKL---KSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQ 1130
            ||:|:||.||..:.   ...:...|:|:.......::...||:||.:::...||||:.||||.:.
Mouse  1066 IGKGHFGVVYHGEYTDGAQNQTHCAIKSLSRITEVQEVEAFLREGLLMRGLHHPNILALIGIMLP 1130

  Fly  1131 KQPI-MIVMELVLGGSLLTYLR--------------KNSNGLTTRQQMGMC------RD------ 1168
            .:.: .:::..:..|.||.::|              ..|.....|..:.:|      :|      
Mouse  1131 PEGLPRVLLPYMRHGDLLHFIRSPQRVSDHCPGWEVSASTHPCLRSPVTLCPQNPTVKDLVSFGL 1195

  Fly  1169 -AAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSR---EEEEYIVSDGM-KQIPVKWTA 1228
             .|.||.||..:..:|||||||||::|...:||::|||::|   ::|.|.|.... .::||||.|
Mouse  1196 QVACGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARGVLDKEYYSVRQHRHARLPVKWMA 1260

  Fly  1229 PEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLM 1293
            .|:|...::|:..||||:|:|:||:.::|..||..:........:..|.|:|.|:..|:.:|.:|
Mouse  1261 LESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQGRRLPQPEYCPDSLYHVM 1325

  Fly  1294 LQCWAADAESRPHFD----EIYNVVDALI 1318
            |:||.||..:||.|.    |:..||.:|:
Mouse  1326 LRCWEADPAARPTFRALVLEVKQVVASLL 1354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FERNP_524288.3 F-BAR_Fes_Fer 7..243 CDD:153341
SH2_Fps_family 953..1039 CDD:198224
TyrKc 1063..1311 CDD:197581 88/280 (31%)
PTKc_Fes_like 1067..1315 CDD:270637 89/284 (31%)
Mst1rXP_006511717.1 Sema_RON 29..525 CDD:200540
PSI 528..570 CDD:214655
IPT 571..685 CDD:387656
IPT_plexin_repeat2 686..770 CDD:238584
IPT 771..864 CDD:214657
PKc_like 1064..1352 CDD:389743 90/285 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100013
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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