DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and Pstpip2

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_038859.3	Gene:	Pstpip2 / 19201	MGIID:	1335088	Length:	334	Species:	Mus musculus

Alignment Length:	268	Identity:	59/268 - (22%)
Similarity:	102/268 - (38%)	Gaps:	66/268 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RLMETMKRSIQMKAKCDKEYAISLTAVAQQGLKIDRADEMQGSLISKSWRSYMDELDHQAK-QFK 88
            |.:|..|:.:...|:|..:.|.:|   .::..|::...|.| .|..|...:.||....|.. |||
Mouse    75 RALEVFKQQVDNVAQCHIQLAQTL---REEARKMEEFREKQ-KLQRKKTETIMDAAHKQRNAQFK 135

  Fly    89 --FNAEQ-LEVVC-DKLTHLSQDKRKARKAYQEEHAKIAARLNHLTDEVVRKKSEYQKHLEGYKA 149
              .:|:: .|..| ||........|.|..|.|.:..|:..:|......|......|..|:...:.
Mouse   136 KAMDAKKNYEQKCRDKDEAEQAVHRSANVANQRQQEKLFVKLATSKTAVEDSDKAYMLHINMLEK 200

  Fly   150 LRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKLHLTHNEYVLSITEAIEVEK--DFRNVLLPGL 212
            :|                  :|.:.::.|||            .:.||.|.|:  .|||.
Mouse   201 VR------------------EDWQSEHIKAC------------EVFEAQECERINFFRNA----- 230

  Fly   213 LEHQQSVQESFILLWRNILQEAAQYGDLTADKYKEIQKRIDTVIGSINPTEEYGEFTEKYKT--S 275
                         ||.: |.:.:|......:.|::::|.::|.  ||....:|  |..:.||  :
Mouse   231 -------------LWLH-LNQLSQQCVANDEMYEQVRKSLETC--SIEKDIQY--FVNQRKTGQT 277

  Fly   276 PTTPLLFQ 283
            |..|::::
Mouse   278 PPAPIMYE 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341	48/224 (21%)
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
Pstpip2	NP_038859.3	F-BAR_PSTPIP2	15..254	CDD:153356	49/231 (21%)
Pstpip2	NP_038859.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	288..322
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910